Rchr
J-GLOBAL ID：202001004093455586
Update date: Oct. 08, 2024
Nakajima Kichitaro
ナカジマ キチタロウ | Nakajima Kichitaro
Affiliation and department：
Research field (3)：
Basic physical chemistry
, Machine materials and mechanics
, Applied physics - general
Research keywords (3)：
アミロイド線維
, amyloidosis
, Sonochemistry
Research theme for competitive and other funds (7)：
- 2024 - 2029 Deep-learning generation of high-resolution ultrasound images of cultured cells and systematic study of local mechanical stimulation on them by focused ultrasound and their responses
- 2024 - 2026 ハイスループットアミロイドアッセイを実現する音響マイクロデバイス開発
- 2022 - 2025 Nucleation mechanism of amyloid fibril and effects of relevant biological factors
- 2023 - 2024 アミロイド蛋白質の音波物性分析のための超音波装置の開発
- 2021 - 2022 超小型超音波アミロイド生成・分析装置の開発
- 2020 - 2022 Ultrasonically specific amplification of amyloid fibril seeds of neurodegenerative proteins
- 2020 - 2021 超音波化学反応を駆使した神経変性疾患早期診断装置
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Papers (22)：
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Kichitaro Nakajima, Tomoki Ota, Hajime Toda, Keiichi Yamaguchi, Yuji Goto, Hirotsugu Ogi. Surface Modification of Ultrasonic Cavitation by Surfactants Improves Detection Sensitivity of α-Synuclein Amyloid Seeds. ACS Chemical Neuroscience. 2024
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Suguru Yamamoto, Keiko Yamamoto, Yoshitoshi Hirao, Keiichi Yamaguchi, Kichitaro Nakajima, Mami Sato, Miho Kawachi, Mio Domon, Kei Goto, Kentaro Omori, et al. Mass spectrometry-based proteomic analysis of proteins adsorbed by hexadecyl-immobilized cellulose bead column for the treatment of dialysis-related amyloidosis. Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis. 2024. 1-11
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Yuji Goto, Kichitaro Nakajima, Suguru Yamamoto, Keiichi Yamaguchi. Supersaturation, a critical factor underlying proteostasis of amyloid fibril formation. Journal of molecular biology. 2024. 168475-168475
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Lianjie Zhou, Touko Hajiri, Kichitaro Nakajima, César Aguirre, Kensuke Ikenaka, Hideki Mochizuki, Keiichi Yamaguchi, Yuji Goto, Hirotsugu Ogi. Ultrastiff Amyloid-Fibril Network of α-Synuclein Formed by Surface Seeding Reaction Confirmed by Multichannel Electrodeless Quartz-Crystal-Microbalance Biosensor. ACS Sensors. 2023
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Chi-Jing Choong, César Aguirre, Keita Kakuda, Goichi Beck, Hiroki Nakanishi, Yasuyoshi Kimura, Shuichi Shimma, Kei Nabekura, Makoto Hideshima, Junko Doi, et al. Phosphatidylinositol-3,4,5-trisphosphate interacts with alpha-synuclein and initiates its aggregation and formation of Parkinson's disease-related fibril polymorphism. Acta neuropathologica. 2023. 145. 5. 573-595
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MISC (11)：
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中島吉太郎, 山口圭一, 荻博次, 後藤祐児. 超音波を利用した蛋白質アミロイド凝集誘導装置HANABI. 超音波テクノ. 2021
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山口圭一, 中島吉太郎, 後藤祐児. ポリリン酸が引き起こすアミロイド線維形成機構. 月刊「細胞」. 2021
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中島吉太郎, 荻博次. 超音波によるタンパク質凝集加速反応の周波数依存性. 超音波テクノ. 2019
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山田晃大朗, 中島吉太郎, 荻博次, 平尾雅彦. 全反射蛍光顕微鏡とQCMの融合によるアルツハイマー病ペプチドの凝集及び融解ダイナミクスの究明. 超音波テクノ. 2016. 28. 6. 97-101
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NAKAJIMA Kichitaro, OGI Hirotsugu, HIRAO Masahiko, GOTO Yuji. 1C12 Study on nucleation reaction of amyloid β peptide induced by ultrasonic cavitation. 2016. 2016. 28. "1C12-1"-"1C12-5"
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Education (4)：
- 2015 - 2017 Osaka University
- 2014 - 2015 Osaka University
- 2012 - 2014 Osaka University
- 2007 - 2012 Wakayama National College of Technology
Work history (6)：
Committee career (1)：
- 2019/04 - 2020/03 超音波エレクトロニクスの基礎と応用に関するシンポジウム 現地実行委員
Awards (2)：
- 2023/07 - 日本蛋白質科学会 若手奨励賞優秀賞 Research on Risk Factors for the Onset of Amyloidosis by Ultrasonic Amyloid Inducer
- 2020/12 - Symposium on UltraSonic Electronics (USE2020) Young Scientist Award ”High-throughput sonochemical reactor for accelerative amplification of ultratrace amyloid-fibril seeds”
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