- 2024 - 2027 炎症を抑制する新規の好酸球サブセットに着眼した好酸球性胃腸炎の病態解明
- 2022 - 2025 腸粘膜の透過性制御に着目したヒト腸管疑似モデルによる好酸球性胃腸炎の病態解明
- 2021 - 2024 腸管粘膜透過性を制御するB細胞機能の解析とクローン病の病態解明
- 2019 - 2023 Development of a low invasive and non-bioptic diagnostic technique for eosinophil esophagitis by Raman spectroscopy
- 2019 - 2022 経皮感作による食道・皮膚間の免疫応答に着目した好酸球性食道炎の発症機序の解明
- 2019 - 2022 A research for investigating the mechanism how highly pathogenic oral bacteria induces eosinophilic esophagitis.
- 2018 - 2021 Elucidation of a novel mechanism leading regulatory B cells dysfunction of in Crohn's disease
- 2017 - 2020 Avoidance of milk fat globule-epidermal growth factor-8 (MFG-E8) tumor immunity via regulatory B cells and application of mechanism for colon cancer therapy
- 2014 - 2017 Elucidation of the molecular mechanism of induction/activation of regulatory B cells and its application to regulation of intestinal inflammation
- 2011 - 2013 Role of regulatory B cells in chronic intestinal inflammation: association with pathogenesis of Crohn's disease
- 2010 - 2012 食道幹細胞を用いたバレット食道発生機序の解明
- 2008 - 2010 Investigation regarding the role of MFG-E8 on NF-κB-dependent intestinal inflammation : Development of a new anti-inflammatory targeting MFG-E8
- 2006 - 2007 食道幹細胞培養モデルを用いたバレット食道の発生機構の解明
- 2006 - 2007 Evaluation of the role of TRAIL induced cell migration and invasion in cholangioma cells
- 2005 - 2006 Role of negative regulators for Toll-like receptor-dependent signaling in gut innate immune system
- 2005 - 2006 Roles of growth factors and transcriptional factors in the pathophysiology of Barrett's esophagus and Barrett's carcinogenesis
- 2004 - 2005 Establishment of Barrett's esophagus model using stem cell of esophagus
- 2003 - 2004 Essential role of MD-2 in TLR4-dependent signaling during Helicobacter pylori- associated gastritis
- 2001 - 2002 Role of MD-2 in Tool-like receptor 4-dependent signaling in Helicobacter-pylori-associated gastritis
- 1999 - 2000 Methylation in the promoter of TGF-β1 gene in colon mucosa
- 1998 - 1999 ヘリコバクター胃炎における胃粘膜萎縮発生機序の解明-Fasを介したアポトーシスの関与-
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