Rchr
J-GLOBAL ID:202001005450752213   Update date: Feb. 20, 2026

Sasaki Koichi

ササキ コウイチ | Sasaki Koichi
Affiliation and department:
Job title: Postdoc
Research field  (4): Chemical biology ,  Nanobioscience ,  Biomaterials ,  Biomedical engineering
Research keywords  (5): Bio-conjugation Chemistry ,  Protein Engineering ,  Mammalian Cell Engineering ,  Cancer Immunotherapy ,  Drug Delivery System
Research theme for competitive and other funds  (2):
  • 2021 - 2023 Creating 5th generation CAR-T cell for cold and solid tumor therapy
  • 2017 - 2020 自家抗体をがん治療に起用するペプチド性中分子の開発
Papers (21):
  • Koichi Sasaki, Vipul Bhatia, Yuta Asano, Jakob Bakhtiari, Pooja Kaur, Chuyi Wang, Takumi Matsuo, Olivier Dubois, Po-Chuan Chiu, Donny Gun, et al. Collagen-binding IL-12-armoured STEAP1 CAR-T cells reduce toxicity and treat prostate cancer in mouse models. Nature Biomedical Engineering. 2025
  • Koichi Sasaki, Vipul Bhatia, Yuta Asano, Jakob Bakhtiari, Pooja Kaur, Chuyi Wang, Takumi Matsuo, Maria Nikolaidi, Po-Chuan Chiu, Olivier Dubois, et al. Collagen-binding IL-12 expressing STEAP1 CAR-T cells reduce toxicity and eradicate mouse prostate cancer in combination with checkpoint inhibitors. 2025
  • Bhatia, V, Kamat, NV, Pariva, TE, Wu, L-T, Tsao, A, Sasaki, K, Sun, H, Javier, G, Nutt, S, Coleman, I, et al. Targeting advanced prostate cancer with STEAP1 chimeric antigen receptor T cell and tumor-localized IL-12 immunotherapy. Nature Communications. 2023. 14. 1. 2041-2041
  • Koichi Sasaki. HARNESSING TUMOR LOCALIZED IL-12 TO ENHANCE STEAP1 CAR T CELL THERAPY FOR PROSTATE CANCER. Journal for ImmunoTherapy of Cancer. 2022
  • Srinivas Balagopal, Koichi Sasaki, Pooja Kaur, Maria Nikolaidi, Jun Ishihara. Emerging approaches for preventing cytokine release syndrome in CAR-T cell therapy. Journal of Materials Chemistry B. 2022
more...
Professional career (1):
  • PhD (Engineering) (Kyushu University)
Work history (6):
  • 2025/02 - 現在 Department of Bioengineering, Imperial College London Research Fellow
  • 2023/02 - 2025/01 Department of Bioengineering, Imperial College London EMBO Postdoctoral Fellow
  • 2021/04 - 2023/01 Department of Bioengineering, Imperial College London JSPS Overseas Research Fellow
  • 2020/04 - 2021/03 Osaka Prefecture University Department of Applied Chemistry Postdoc
  • 2017/04 - 2020/03 Kyushu University Graduate School of Engineering JSPS Research Fellow (PhD student)
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Awards (12):
  • 2025/02 - Career Acceleration Fellowship Prostate Cancer UK
  • 2024/12 - Imperial College London Wings for Ideas Fund 2025
  • 2022/06 - EMBO Postdoctoral Fellowship
  • 2022/06 - Selected participant for the 71st Lindau Nobel Laureate Meeting
  • 2022/05 - The 5th International Union of Materials Research Societies-International Conference of Young Researchers on Advanced Materials (IUMRS-ICYRAM2022) Travel Award
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