Rchr

J-GLOBAL ID：202001005934727540 Update date: Oct. 30, 2024

SATOH KENNICHI

サトウケンイチ | SATOH KENNICHI

Affiliation and department：
Job title：教授

Research field (1)： Gastroenterology

Research keywords (3)： Molecular pathology , Pancreatic cancer , Gastroenterology

Research theme for competitive and other funds (47)：

2024 - 2027 Elucidation of a novel mechanism of the regeneration of endocrine cells from unusual pancreatic ductal cells
2023 - 2026 一般検診の基本的データを用いた人工知能による膵癌マススクリーニング法の確立
2022 - 2025 新規SRC制御分子FAXCによる肝内胆管癌幹細胞の維持機構
2019 - 2022 A new approach to the pathogenesis of pancreatic cancer and the disorders of circadian rhythm based on the analysis of CRY1-binding proteins
2018 - 2021 The development of novel molecular therapy targeting to carcinoma- stroma interaction and heterogeneity of advanced pancreatic cancer.

2018 - 2021 The tumor initiating cell asa new therapeutic target for hypopharyngeal cancer.

2017 - 2020 Target therapy for cancer-associated fibroblast in pancreatic cancer

2017 - 2020 A new targeting therapy against periostin in lung cancer

2017 - 2020 Development of non-coding RNA-targeting therapy for refractory renal carcinoma

2015 - 2019 The establishment of new therapy targeting metabolic characteristics and cancer-stroma interaction for pancreatic cancer

2015 - 2018 Elucidation the roles of senescence-like phenotype in pancreatic beta-cells in diabetic mutant cryptochrome1 transgenic mice

2015 - 2018 Actin cytoskeleton control by a HNSCC stem cell marker CD271

2015 - 2018 Establishment of a specific therapy for lung cancer stem cells

2015 - 2017 Validation of CD271 as a Therapeutic Target of Squamous Cell Carcinoma

2015 - 2017 Survival mechanism of CD271-positive HNSCC and itstherapeutic intervention

2014 - 2017 Identification of PKM as a target for pancreatic cancer therapy

2013 - 2015 The development of the therapy for metastatic pancreatic cancer targeting its microenvironment.

2013 - 2015 Generation of artificial lung cancer stem cells and its regulation by microenvironment in order to develop the effective therapeutic strategy for lung cancer.

2012 - 2015 Roles for pyruvate kinase M in tumorigenesis

2012 - 2015 Regulatory mechanism for intracellar traficking of the membrane-bound NEU3 sialidase

2012 - 2015 Generation of artificial pancreatic cancer stem cell and its regulation by microRNA in order to develop effective therapy for pancreatic cancer.

2012 - 2015 Identification of a Cancer stem cell marker and therapeutic target by xenotlansplantation methods

2012 - 2014 Possible interdependence between Warburg effect and genomic instability during colorectal cancer development

2012 - 2014 Targeting continuous inflammation in pancreatic cancer microenvironment

2012 - 2014 Establishment of patient-derived non-small cell lung cancer xenografts as model for enrichment of cancer stem cell, and identification of lung cancer stem cell.

2011 - 2014 Novel therapeutic strategy targeting pancreatic cancer stem cell-niche

2011 - 2013 Stellate cell-mediated regulation of stemness maintenance in pancreatic cancer stem cells

2011 - 2013 Analysis of Head and Neck Cancer malignancy related to EMT and Cancer Stem Cells

2010 - 2011 Identification and clinical application of cancer stem cell inhibitory microRNA

2009 - 2011 Development of the new therapy targeted for pancreatic cancer stem cell and cancer cells with EMT status via induction of cellular senescence

2009 - 2011 Bone marrow derived cells in the experimental mouse pancreatic cancer.

2009 - 2010 The genetic change of pancreatic duct epithelial cells mediated by epithelial mesenchymal transition

2008 - 2010 Invasive pancreatic cancer specific apoptosis induction therapy by microRNA.

2008 - 2010 Elucidation of the pathogenesis of alcoholic pancreatitis and development of its prevention

2008 - 2010 Elucidation of the micro-RNA-mediated regulation of pancreatic stellate cell activation and its therapeutic applications.

2007 - 2008 Development of pancreatic cancer stem cell targeted therapy using cells derived from bone marrow

2007 - 2008 Development of the gene therapy against pancreatic cancer by using the MSX2-restricted vector

2006 - 2007 Activation of pancreatic stellate cells mediated by Toll-like receptor

2005 - 2007 The identification of the factors which enhance EMT in PanIN and the establishment of therapeutic approach to induce pancreatic carcinoma differentiation

2004 - 2005 Development of new therapy targetting pancreatic cancer-stellate cell interaction

2004 - 2005 ISFETを用いた膵管内PHモニタの作成と膵炎、膵癌の早期診断への応用

2003 - 2004 Elucidation of mechanisms of pancreatic oncogenesis and establishment of novel therapy by modulating Notch signaling

2000 - 2003 Fiber-optic approaches for diagnosis of gastrointestinal disease

1999 - 2001 Development of a novel therapy for severe acute pancreatitis by a specific inhibiiton of NF-κB- -Basic analysis using recombinant NLS-I k Bαadenoviral vector-

1999 - 2000 膵臓癌に対する内視鏡的遺伝子治療開発のための目的遺伝子の同定

1997 - 1998 膵臓癌治療法確立のための膵臓癌浸潤転移機構のシグナル伝達系の解明

1996 - 1997 Study for the molecular pathogenesis of the idiopathic chronic pancreatitis, especially familial pancreatitis

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Papers (182)：

小岩井明信, 廣田衛久, 猪股奈々, 高須充子, 佐藤賢一. 若手消化器内視鏡専門医からのメッセージ悪性遠位胆管狭窄に対するMulti-hole SEMSの有用性. 日本消化器内視鏡学会東北支部例会. 2024. 172回. 58-58
猪股奈々, 小岩井明信, 廣田衛久, 高須充子, 佐藤賢一. 膵・胆道疾患に対する内視鏡診療の進歩当院での良性胆管空腸吻合部狭窄に対する治療成績と金属ステントの有用性の検討. 日本消化器内視鏡学会東北支部例会. 2024. 172回. 62-62
住谷秀仁, 小岩井明信, 廣田衛久, 高須充子, 佐藤賢一. 急性膵炎を契機に発見された膵管癒合不全を伴う腹側膵回転異常の1例. 膵臓. 2023. 38. 5. 348-354
宮下優輝, 小岩井明信, 廣田衛久, 桜井博仁, 高見一弘, 山本久仁治, 片寄友, 佐藤賢一. 胆嚢癌内に発生し,胆道出血を来した右肝動脈・胆嚢動脈分岐部仮性動脈瘤破裂の一例. 胆道. 2023. 37. 3. 454-454
高見一弘, 桜井博仁, 近藤典子, 山本久仁治, 小岩井明信, 廣田衛久, 佐藤賢一, 片寄友. 膵頭十二指腸切除術後における良性胆管空腸吻合部狭窄に対しBONASTENT M-Intraductalを使用した8例の検討. 胆道. 2023. 37. 3. 471-471

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MISC (271)：

金諒, 遠藤克哉, 佐藤倫紀, 吉野祐貴, 川上瑶子, 村上圭吾, 村上一宏, 佐藤賢一. 先行する内視鏡的切除により病理組織学的に詳細な術前診断を行った回腸神経内分泌腫瘍の一例. 日本消化器内視鏡学会東北支部例会. 2022. 168回. 81-81
宮下優輝, 遠藤克哉, 村上圭吾, 金諒, 佐々木義輝, 佐藤倫紀, 川上瑶子, 村上一宏, 佐藤賢一. 悪性リンパ腫に極めて類似する興味ある内視鏡像を呈した上行結腸粘液癌の1例. 日本消化器病学会東北支部例会・日本消化器内視鏡学会東北支部例会プログラム・抄録集. 2022. 212回・167回. 170-170
片山智文, 小岩井明信, 廣田衛久, 金諒, 川村恵太, 高須充子, 目黒敬義, 村上圭吾, 佐藤賢一. 5年以上経過観察された膵嚢胞性病変から発生したIPMN由来浸潤癌(pancreatobiliary type)に同時多中心性発癌(IPMN隣接併存膵癌)を認めた一例. 日本消化器病学会東北支部例会誌. 2022. 212th
金諒, 小岩井明信, 廣田衛久, 片山智文, 川村恵太, 高須充子, 目黒敬義, 村上圭吾, 佐藤賢一. 自己免疫性膵炎発症後15年の経過を経て発見され,EUS-FNBにて診断したIgG4関連肝炎症性偽腫瘍の一例. 日本消化器病学会東北支部例会誌. 2022. 212th
小岩井明信, 廣田衛久, 佐藤賢一. 経口胆道鏡における新世代内視鏡システム(EVIS X1/RDI)の有用性. 日本消化器病学会東北支部例会誌. 2022. 212th

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Education (1)：

1982 - 1988 Tohoku University Faculty of Medicine School of Medicine

Work history (8)：

2017/04 - 現在 Tohoku Medical and Pharmaceutical University
2011/04 - 2017/03 Miyagi Prefectural Hospital Organization Miyagi Cancer Center
2010/09 - 2011/03 Miyagi Prefectural Hospital Organization Miyagi Cancer Center
2009/04 - 2010/08 東北大学病院消化器内科講師
2003/10 - 2009/03 東北大学病院消化器内科院内講師

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Committee career (4)：

2012/01 - 現在日本膵臓学会編集委員
2012/01 - 現在日本癌学会評議員
2011/05 - 現在日本膵臓学会学会評議員
2004/01 - 現在日本消化器病学会学会評議員

Association Membership(s) (6)：

日本胆道学会 , 日本肝臓学会 , 日本癌学会 , 日本消化器内視鏡学会 , 日本内科学会 , 日本膵臓学会

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