Niwa Yasuo

ニワヤスオ | Niwa Yasuo

Affiliation and department：
Job title：教授

Research field (1)： Molecular biology

Research theme for competitive and other funds (13)：

2015 - 2018 Studies on the efficacy of toxin neutralization and safety of Shiga toxin-specific secretory IgA type plantibody produced by practical plants
2013 - 2015 Mucosal surface defense by edible IgA produced by plants
2011 - 2012 Expression of secretory immunoglobulin A in lettuce suitable for the production of therapeutic antibodies in plantfactory.
2007 - 2008 分泌経路が関わる色素体分化制御メカニズムの解明
2000 - 2002 Mechanisms of response to environmental stresses with active oxygen species-detoxification in higer plants

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Papers (52)：

Katsuhiro Nakanishi, Taichi Takase, Yuya Ohira, Ryota Ida, Noriko Mogi, Yuki Kikuchi, Minami Matsuda, Kohta Kurohane, Yoshihiro Akimoto, Junri Hayakawa, et al. Prevention of Shiga toxin 1-caused colon injury by plant-derived recombinant IgA. Scientific Reports. 2022. 12. 1. 17999-17999
Katsuhiro Nakanishi, Noriko Mogi, Yuki Kikuchi, Minami Matsuda, Takeshi Matsuoka, Kotome Shiina, Shota Morikane, Kohta Kurohane, Yasuo Niwa, Hirokazu Kobayashi, et al. Plant-derived secretory component gives protease-resistance to Shiga toxin 1-specific dimeric IgA. Plant Molecular Biology. 2021. 106. 3. 297-308
Katsuhiro Nakanishi, Minami Matsuda, Ryota Ida, Nao Hosokawa, Kohta Kurohane, Yasuo Niwa, Hirokazu Kobayashi, Yasuyuki Imai. Lettuce-derived secretory IgA specifically neutralizes the Shiga toxin 1 activity. Planta. 2019. 250. 4. 1255-1264
Katsuhiro Nakanishi, Shota Morikane, Nao Hosokawa, Yuka Kajihara, Kohta Kurohane, Yasuo Niwa, Hirokazu Kobayashi, Yasuyuki Imai. Plant-derived secretory component forms secretory IgA with shiga toxin 1-specific dimeric IgA produced by mouse cells and whole plants. Plant cell reports. 2019. 38. 2. 161-172
Makoto T Fujiwara, Mana Yasuzawa, Kei H Kojo, Yasuo Niwa, Tomoko Abe, Shigeo Yoshida, Takeshi Nakano, Ryuuichi D Itoh. The Arabidopsis arc5 and arc6 mutations differentially affect plastid morphology in pavement and guard cells in the leaf epidermis. PloS one. 2018. 13. 2. e0192380

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MISC (63)：

茂木典子, 中西勝宏, 黒羽子孝太, 菊地祐希, 松田弥奈美, 森兼捷太, 丹羽康夫, 小林裕和, 今井康之. Digestive enzyme resistance of secretory IgA is created by plant-derived secretory component in vitro. 日本薬学会年会要旨集(CD-ROM). 2020. 140th
井田涼太, 松田弥奈美, 中西勝宏, 黒羽子孝太, 丹羽康夫, 小林裕和, 今井康之. レタスで作製した志賀毒素特異的IgA植物抗体の抗原結合性と毒素中和活性の評価. 日本薬学会年会要旨集(CD-ROM). 2019. 139th
大平裕也, 梶原優佳, 森兼捷太, 中西勝宏, 黒羽子孝太, 丹羽康夫, 小林裕和, 今井康之. 植物で作製した分泌片への小胞体保留シグナル配列の付加:植物型糖鎖の削減. 日本薬学会年会要旨集(CD-ROM). 2019. 139th
中西勝宏, 井田涼太, 松田弥奈美, 細川奈緒, 黒羽子孝太, 丹羽康夫, 小林裕和, 今井康之. レタス緑色組織特異的な志賀毒素に対する分泌型IgAの発現. 日本植物細胞分子生物学会大会・シンポジウム講演要旨集. 2019. 37th
菊地祐希, 松田弥奈美, 森兼捷太, 中西勝宏, 黒羽子孝太, 丹羽康夫, 小林裕和, 今井康之. 分泌型IgAのペプシン抵抗性:植物由来組換え型分泌片を用いた研究. 日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会講演要旨集. 2018. 2018

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Patents (4)：

Education (2)：

Work history (11)：

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Committee career (3)：

Awards (4)：

2008 - J. Biosci. Bioeng. paper award Development of series of Gateway binary vectors, pGWBs, for realizing efficient construction of fusion genes for plant transformation
2007 - BBB paper award Improved Gateway binary vectors: High-performance vectors for creation of fusion constructs in transgenic analysis of plants
2005/09 - 日本植物学会特別賞「植物分子生物学における緑色蛍光タンパク質の開発・普及に対して」
2001/07 - 日本植物細胞分子生物学会(現日本植物バイオテクノロジー学会) 奨励賞「植物GFPの改良とその利用法の開発に関する研究」

Association Membership(s) (2)：

清沢神楽保存会・静岡県文化財保存協会 , 日本分子生物学会・日本植物学会・日本植物生理学会・日本植物バイオテクノロジー学会・The Society for Experimental Biology

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