Rchr
J-GLOBAL ID:202001007587820189   Update date: Aug. 29, 2024

Osanai Yasuyuki

オサナイ ヤスユキ | Osanai Yasuyuki
Affiliation and department:
Job title: Assistant professor
Research theme for competitive and other funds  (7):
  • 2024 - 2027 髄鞘形成を介した感覚代償の制御機構解明と誘導法の開発
  • 2023 - 2024 感覚機能代償における髄鞘の機能解析
  • 2021 - 2024 新規オリゴデンドロサイト-神経軸索同時標識法の開発と応用
  • 2020 - 2022 Analysis of oligodendrocyte functions for the optic nerve development
  • 2021 - 2022 Investigation of oligodendrocyte functions in visual diseases
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Papers (17):
  • Yasuyuki Osanai, Yao Lulu Xing, Shinya Mochizuki, Kenta Kobayashi, Jihane Homman-Ludiye, Amali Cooray, Jasmine Poh, Ayumu Inutsuka, Nobuhiko Ohno, Tobias D. Merson. 5′ Transgenes drive leaky expression of 3′ transgenes in Cre-inducible bi-cistronic vectors. Molecular Therapy - Methods and Clinical Development. 2024. 32. 3. 101288-101288
  • Yao Lulu Xing, Jasmine Poh, Bernard H A Chuang, Kaveh Moradi, Stanislaw Mitew, William D Richardson, Trevor J Kilpatrick, Yasuyuki Osanai, Tobias D Merson. High-efficiency pharmacogenetic ablation of oligodendrocyte progenitor cells in the adult mouse CNS. Cell reports methods. 2023. 3. 2. 100414-100414
  • Reiji Yamazaki, Yasuyuki Osanai, Tom Kouki, Jeffrey K Huang, Nobuhiko Ohno. Pharmacological treatment promoting remyelination enhances motor function after internal capsule demyelination in mice. Neurochemistry international. 2023. 164. 105505-105505
  • Batpurev Battulga, Kazuhiro Shiizaki, Yutaka Miura, Yasuyuki Osanai, Reiji Yamazaki, Yoshiaki Shinohara, Yoshiyuki Kubota, Toru Hara, Makoto Kuro-O, Nobuhiko Ohno. Correlative light and electron microscopic observation of calcium phosphate particles in a mouse kidney formed under a high-phosphate diet. Scientific reports. 2023. 13. 1. 852-852
  • Yasuyuki Osanai, Batpurev Battulga, Reiji Yamazaki, Tom Kouki, Megumi Yatabe, Hiroaki Mizukami, Kenta Kobayashi, Yoshiaki Shinohara, Yumiko Yoshimura, Nobuhiko Ohno. Dark Rearing in the Visual Critical Period Causes Structural Changes in Myelinated Axons in the Adult Mouse Visual Pathway. Neurochemical research. 2022. 47. 9. 2815-2825
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MISC (14):
  • 長内康幸. オリゴデンドロサイトによる神経可塑性の制御. 月刊「細胞」 55(10) p53-55 2023年9月. 2023
  • 稲垣健志, 山崎礼二, 長内康幸, 東森生, 鈴木秀人, 大野伸彦, 大野伸彦. 脳細動脈硬化における血管線維化と脳血管周囲マクロファージの役割. 日本臨床分子形態学会総会・学術集会講演プログラム・要旨集. 2023. 55th
  • 山崎礼二, 長内康幸, 幸喜富, 大野伸彦, 大野伸彦. Clemastine improves motor dysfunction caused by internal capsule demyelination in mice. 日本解剖学会総会・全国学術集会抄録集(CD-ROM). 2023. 128th
  • 長内康幸, 長内康幸, BATPUREV Battulga, 高瀬堅吉, 山崎礼二, 幸喜富, 矢田部恵, 菊地元史, 水上浩明, 小林憲太, et al. 視覚遮断による髄鞘構造の変化と行動異常の解析. 日本解剖学会総会・全国学術集会抄録集(CD-ROM). 2023. 128th
  • OSANAI Yasuyuki, OSANAI Yasuyuki, BATTULGA Batpurev, YAMAZAKI Reiji, KOUKI Tom, YATABE Megumi, SHINOHARA Yoshiaki, OHNO Nobuhiko, OHNO Nobuhiko. Identification of neuronal subtypes that are myelinated by a single oligodendrocyte. 日本組織細胞化学会総会・学術集会講演プログラム・予稿集. 2022. 63rd (CD-ROM)
more...
Lectures and oral presentations  (3):
  • Length of myelin internodes of oligodendrocytes is controlled by microenvironment influenced by axonal activity in sensory derived mouse model.
    (2019 Meeting of the Austrasian Neuroscience Society, 39th Annual Scientific Meeting. 2019)
  • Rabies virus-mediated oligodendrocyte labeling reveals a single oligodendrocyte myelinates axons by sensing neuronal subtypes.
    (ARMI seminar, Monash University 2016)
  • Oligodendrocytes myelinate axons by sensing neuronal subtypes and/or sensory inputs with individual variance in selectivity.
    (The 8th Nagoya global retreat. (February 13th 2016, Higashiura, Japan) 2016)
Professional career (1):
  • PhD (The Graduate University for Advanced Studies)
Work history (8):
  • 2022/11 - 現在 自治医科大学医学部解剖学講座組織学部門 講師
  • 2020/04 - 2022/10 Asst prof, Jichi Medical University (Prof Nobuhiko Ohno lab)
  • 2017/05 - 2020/03 Research fellow, Monash University (Dr Toby Merson lab)
  • 2015/04 - 2017/04 Postdoctoral fellow in NIPS (Prof Kazu Ikenaka lab)
  • 2012/04 - 2015/03 PhD in The Graduate University for Advanced Studies
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Awards (4):
  • 2024/06 - 公益社団法人 新化学技術推進協会 第13回新化学技術研究奨励賞
  • 2024/02 - The 8th Japanese Myelin Meeting The Award for Excellent Presentation
  • 2022/09 - Jichi Medical Unibversity JMU symposium presentation award
  • 2016/09 - Japanese Society for Neurochemistry Best young oral presentation
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