MORIMOTO SATORU

Research theme for competitive and other funds (10)：

2022 - 2027 D2R-mediated Gs/Gi rebalancing in ALS motor neurons
2021 - 2026 Mechanism and application of Hero proteins
2022 - 2025 ALS運動ニューロン標的iPS細胞創薬から同定された薬物のグリア細胞疾患修飾作用
2018 - 2023 ALS/PDC - 世界3大多発地での環境と遺伝子の cross talk -
2019 - 2022 A novel treatment of cerebral infarction with neuroprotective astrocytes induced by inflammatory microglia

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Papers (89)：

Kensuke Okada, Daisuke Ito, Satoru Morimoto, Chris Kato, Yuki Oguma, Hitoshi Warita, Naoki Suzuki, Masashi Aoki, Junko Kuramoto, Reona Kobayashi, et al. Multiple lines of evidence for disruption of nuclear lamina and nucleoporins in FUS amyotrophic lateral sclerosis. Brain. 2024
Chris Kato, Satoru Morimoto, Shinichi Takahashi, Shinichi Namba, Qingbo S Wang, Yukinori Okada, Hideyuki Okano. Spinal cord motor neuron phenotypes and polygenic risk scores in sporadic amyotrophic lateral sclerosis: deciphering the disease pathology and therapeutic potential of ropinirole hydrochloride. Journal of Neurology, Neurosurgery & Psychiatry. 2024. jnnp-2024
Chris Kato, Koji Ueda, Satoru Morimoto, Shinichi Takahashi, Shiho Nakamura, Fumiko Ozawa, Daisuke Ito, Yugaku Daté, Kensuke Okada, Naoki Kobayashi, et al. Proteomic insights into extracellular vesicles in ALS for therapeutic potential of Ropinirole and biomarker discovery. Inflammation and Regeneration. 2024. 44. 1
Nicolas Leventoux, Satoru Morimoto, Mitsuru Ishikawa, Shiho Nakamura, Fumiko Ozawa, Reona Kobayashi, Hirotaka Watanabe, Sopak Supakul, Satoshi Okamoto, Zhi Zhou, et al. Aberrant CHCHD2-associated mitochondriopathy in Kii ALS/PDC astrocytes. Acta neuropathologica. 2024. 147. 1. 84-84
Masanori Kurihara, Tomoyasu Matsubara, Satoru Morimoto, Akira Arakawa, Kensuke Ohse, Kazutomi Kanemaru, Atsushi Iwata, Shigeo Murayama, Yuko Saito. Neuropathological changes associated with aberrant cerebrospinal fluid p-tau181 and Aβ42 in Alzheimer's disease and other neurodegenerative diseases. Acta neuropathologica communications. 2024. 12. 1. 48-48

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MISC (24)：

曾根大地, 森本悟, 中島振一郎, 品川俊一郎. The “Holy Grail” of Neuropsychiatric Medicine: Challenges for Disease-Modifying Therapy. 精神神経学雑誌. 2023. 125. 7. 569-578
高橋愼一, 森本悟, 伊東大介, 伊達悠岳, 岡田健佑, Chyi Muh Chai, 西山亜由美, 鈴木直輝, 平井美和, 加部泰明, et al. 大規模レジストリデータベースを活用したALS治験(ROPALS試験)におけるロピニロール塩酸塩の有効性の検証. 脳循環代謝. 2022. 34. 1. 142-142
栗原正典, 小松大樹, 仙石錬平, 渋川茉莉, 森本悟, 波多野敬子, 井原涼子, 東原真奈, 仁科裕史, 石橋賢士, et al. 非アルツハイマー病におけるAT(N)分類~神経核内封入体病での脳脊髄液p-tau181上昇~. Dementia Japan. 2022. 36. 4
森本悟, 森本悟, 高橋愼一, 高橋愼一, 高橋愼一, 伊東大介, 伊達悠岳, 岡田健佑, CHAI Muh Chyi, CHAI Muh Chyi, et al. iPS細胞創薬に基づいた筋萎縮性側索硬化症(ALS)に対するロピニロール塩酸塩の医師主導治験(ROPALS試験). 神経治療学(Web). 2021. 38. 6
小久保康昌, 森本悟, 佐々木良元, 葛原茂樹, 石神昭人. Abnormal Accumulation of Citrullinated Proteins of Kii ALS/PDC. パーキンソン病・運動障害疾患コングレスプログラム・抄録集. 2019. 13th

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