Rchr
J-GLOBAL ID：202001009803667954
Update date: Apr. 01, 2024
Nakamura Yoshinobu
ナカムラ ヨシノブ | Nakamura Yoshinobu
Affiliation and department：
Homepage URL (1)：
https://www.molecularkinetics.org
Research field (2)：
Molecular biology
, Clinical pharmacy
Research theme for competitive and other funds (4)：
- 2023 - 2027 Analysis of thermoregulatory mechanisms by the CNS using model animals of female-dominant infectious hypothermia
- 2022 - 2025 SLCOトランスポーターをコアとするチャネル活性発現機構の解明
- 2020 - 2022 Elucidation of the mechanisms of subcellular localization of the prostaglandin transporter
- 2019 - 2020 膜リン脂質非対称分布評価に基づくエキソソームの機能解明
Papers (14)：
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Yoshinobu Nakamura, Masa-aki Ito, Yukino Hoshino, Isao Matsuoka, Toshiaki Okada, Yasunobu Okada, Takeo Nakanishi. Modulation of prostaglandin transport activity of SLCO2A1 by annexin A2 and S100A10. American Journal of Physiology-Cell Physiology. 2024
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Takeo Nakanishi, Yuki Kawasaki, Yoshinobu Nakamura, Yuuki Kimura, Kotone Kawamura, Melody N. Shumba, Noriaki Shimokawa. An implication of the mitochondrial carrier SLC25A3 as an oxidative stress modulator in NAFLD. Experimental Cell Research. 2023. 431. 1. 113740-113740
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Yoshinobu Nakamura, Chisato Aizawa, Hinako Kawata, Takeo Nakanishi. N-glycosylation modifies prostaglandin E2 uptake by reducing cell surface expression of SLCO2A1. Prostaglandins & Other Lipid Mediators. 2023. 165. 106714-106714
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Yoshinobu Nakamura, Hina Kozakai, Tsubura Nishio, Kazuki Yoshida, Takeo Nakanishi. Phenolsulfonphthalein as a surrogate substrate to assess altered function of the prostaglandin transporter SLCO2A1. Drug Metabolism and Pharmacokinetics. 2022. 44. 100452-100452
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Tokuji Tsuji, Shin-ya Morita, Yoshinobu Nakamura, Yoshito Ikeda, Taiho Kambe, Tomohiro Terada. Alterations in cellular and organellar phospholipid compositions of HepG2 cells during cell growth. Scientific Reports. 2021. 11. 1
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MISC (2)：
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Hiroaki Shimada, Takeo Nakanishi, Yoshinobu Nakamura, Masahiro Iwaki, Ikumi Tamai. POTENTIAL OF PROSTAGLANDIN TRANSPORTER OATP2A1/SLCO2A1 AS A TARGET OF NOVEL ANTI-INFLAMMATORY DRUG. DRUG METABOLISM AND PHARMACOKINETICS. 2017. 32. 1. S102-S103
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Nakamura Yoshinobu, Nakanishi Takeo, Shimada Hiroaki, Tamai Ikumi. RELEVANCE OF PROSTAGLANDIN TRANSPORTER (PGT) TO PGE(2) SECRETION FROM MACROPHAGES IN RESPONSE TO INFLAMMATORY STIMULATION. DRUG METABOLISM REVIEWS. 2015. 47. 288
Lectures and oral presentations (26)：
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Annexin A2およびS100A10がSLCO2A1のプロスタグランジンE2輸送活性に及ぼす影響
(日本薬学会 第144年会 2024)
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プロスタグランジン輸送体SLCO2A1のMaxi-Clチャネル活性発現機構
(第1回 Transformative Life Science Meeting 2024)
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Do hypotonicity and accessory proteins required for Maxi-Cl channel affect SLCO2A1-mediated prostaglandin E2 transport activity?
(2023 ICCP450/JSSX 2023)
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Maxi-Clアクセサリータンパク質ANXA2およびS100A10がSLCO2A1のプロスタグランジンE2輸送活性に及ぼす影響
(第17回トランスポーター研究会年会 2023)
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輸送体とチャネルのデュアル機能を備えた膜タンパク質がもたらす生理的意義
(Keio Pharmaceutics Research Forum 2023 Frontiers in Biopharmaceutics 2023)
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Education (3)：
- 2016 - 2019 Kanazawa University Institute of Medical and Health Sciences Faculty of Pharmaceutical Sciences
- 2014 - 2016 Kanazawa University Institute of Medical and Health Sciences Faculty of Pharmaceutical Sciences
- 2010 - 2014 Kanazawa University
Professional career (1)：
Work history (3)：
- 2024/04 - 現在 Takasaki University of Health and Welfare Faculty of Pharmacy Department of Pharmacy Lecturer
- 2020/04 - 2024/03 Takasaki University of Health and Welfare Faculty of Pharmacy Department of Pharmacy Assistant professor
- 2019/04 - 2020/03 Shiga University of Medical Science Hospital Department of Pharmacy Postdoctoral researcher
Committee career (1)：
- 2021/05 - 現在 Review Editor Frontiers in Pharmacology
Awards (4)：
- 2020/10 - 第15回 トランスポーター研究会年会 優秀口頭発表賞
- 2019/03 - 金沢大学 学長賞
- 2017/10 - 第39回 生体膜と薬物の相互作用シンポジウム 優秀発表賞
- 2016/03 - 日本薬学会 第136年会 優秀発表賞 (口頭の部)
Association Membership(s) (4)：
日本生理学会
, 日本脂質生化学会
, 日本薬学会
, 日本薬物動態学会
