Rchr
J-GLOBAL ID：202001010227639476
Update date: Oct. 24, 2025
NAKAMURA Ryosuke
ナカムラ リョウスケ | NAKAMURA Ryosuke
Affiliation and department：
Research field (1)：
Pharmaceuticals - health and biochemistry
Research theme for competitive and other funds (5)：
- 2023 - 2026 生薬オンジ由来化合物による抗メチル水銀作用機構の解明
- 2020 - 2023 オレアノール酸サポニン誘導体ライブラリーを用いた新規抗メチル水銀薬の探索
- 2017 - 2019 Development of novel anti-methylmercuric drug based on oleanolic acid glucoside
- 2015 - 2018 Molecular breeding of Arabidopsis plants with cell-type specific promoters and a bacterial mercury transporter MerC
- 2015 - 2017 Search for compounds that supress the effects of low-dose methylmercury
Papers (50)：
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Yasukazu Takanezawa, Kazuma Sakai, Ryosuke Nakamura, Yuka Ohshiro, Shimpei Uraguchi, Masako Kiyono. The predominant role of p62/SQSTM1 over NBR1 in methylmercury-induced cytotoxicity and cellular defense. Biochemical and Biophysical Research Communications. 2025. 151461-151461
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Shimpei Uraguchi, Masakazu Sato, Chihiro Hagai, Momoko Hirakawa, Kotomi Ogawa, Miyu Odagiri, Haruka Sato, Ayaka Ohmori, Yuka Ohshiro, Ryosuke Nakamura, et al. Phenylmercury stress induces root tip swelling through auxin homeostasis disruption. Plant Molecular Biology. 2024. 115. 1
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Ryosuke Nakamura, Takashi Iwai, Yasukazu Takanezawa, Tatsuya Shirahata, Naruki Konishi, Yuka Ohshiro, Shimpei Uraguchi, Mitsuo Tanabe, Yoshinori Kobayashi, Kenji Sakamoto, et al. Oleanolic acid-3-glucoside, a synthetic oleanane-type saponin, ameliorates methylmercury-induced dysfunction of synaptic transmission in mice. Toxicology. 2024. 506. 153867-153867
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Shimpei Uraguchi, Yuka Ohshiro, Kaede Abe, Yuta Tsuchiya, Ryosuke Nakamura, Yasukazu Takanezawa, Masako Kiyono. Root cell-type specific expressions of bacterial mercury transporter MerC and plant SNARE SYP121 fusion protein differentially affect cadmium accumulation patterns of Arabidopsis. SOIL SCIENCE AND PLANT NUTRITION. 2023
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Yasukazu Takanezawa, Ryosuke Nakamura, Yuka Ohshiro, Shimpei Uraguchi, Masako Kiyono. Gadolinium-based contrast agents suppress adipocyte differentiation in 3T3-L1 cells. Toxicology letters. 2023. 383. 196-203
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MISC (89)：
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大橋悠暉, 高根沢康一, 酒井和真, 中村亮介, 大城有香, 浦口晋平, 清野正子. Autophgy response to toxic metal exposure in SH-SY5Y neuroblastoma cells. 衛生薬学・環境トキシコロジー講演要旨集. 2023. 2023
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高根沢康一, 柏野結, 中村亮介, 大城有香, 浦口晋平, 清野正子. Effect of autophagy on methylmercury-induced lipid droplet formation and adipokine expression in 3T3-L1 cells. Journal of Toxicological Sciences. 2023. 48. Supplement (CD-ROM)
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佐藤正和, 浦口晋平, 萬代麻衣, 大城有香, 中村亮介, 高根沢康一, 清野正子. 亜ヒ酸とカドミウム毒性に対するシロイヌナズナ根端分裂組織の応答の特異性. 日本土壌肥料学会講演要旨集(Web). 2023. 69
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浦口晋平, 山村有加, 菅谷翔, 佐藤正和, 大城有香, 中村亮介, 高根沢康一, 清野正子. 根端分裂組織のカドミウム・亜ヒ酸応答におけるNAC型転写因子ANAC044とANAC085の機能分化の可能性. 日本土壌肥料学会講演要旨集(Web). 2023. 69
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土屋佑太, 浦口晋平, 月岡輝璃, 西田翔, 大城有香, 中村亮介, 高根沢康一, 清野正子. 微生物由来の金属輸送体MerC多重発現シロイヌナズナの確立の試み. 日本土壌肥料学会講演要旨集(Web). 2023. 69
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Patents (1)：
Lectures and oral presentations (1)：
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Protective effect of oleanolic acid-3-glucoside on methylmercury toxicity
(NIMD FORUM 2022 2022)
Education (2)：
- 2002 - 2004 Kitasato University Graduate School of Pharmaceutical Sciences
- 1998 - 2002 Kitasato University School of Pharmaceutical Sciences
Work history (2)：
- 2007/04 - 現在 Kitasato University School of Pharmaceutical Sciences
- 2004/04 - 2007/03 Kitasato University School of Pharmacy
Association Membership(s) (2)：
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