Shiba Kahori

Affiliation and department：

Research field (1)： Neuroscience - general

Research theme for competitive and other funds (9)：

2020 - 2023 パーキンソン病原因遺伝子産物VPS13Cによるオートファジー制御機構の解明
2020 - 2023 Elucidation of intracellular environmental factors that produce a risk for alpha-Synuclein seeding
2017 - 2021 Functional analysis of novel molecules involved in PINK1-Parkin-mediated mitophagy
2017 - 2020 Exploration of Parkinson disease-specific pathological background
2016 - 2018 Drug screening to improve mitochondrial functions

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Papers (30)：

Aya Ikeda, Hongrui Meng, Daisuke Taniguchi, Muneyo Mio, Manabu Funayama, Kenya Nishioka, Mari Yoshida, Yuanzhe Li, Hiroyo Yoshino, Tsuyoshi Inoshita, et al. CHCHD2 P14L, found in amyotrophic lateral sclerosis, exhibits cytoplasmic mislocalization and alters Ca2+ homeostasis. PNAS Nexus. 2024. 3. 8
Toshiki Tezuka, Daisuke Taniguchi, Mariko Sano, Tomoyo Shimada, Yutaka Oji, Taiji Tsunemi, Aya Ikeda, Yuanzhe Li, Hiroyo Yoshino, Jun Ogata, et al. Pathophysiological evaluation of the LRRK2 G2385R risk variant for Parkinson's disease. NPJ Parkinson's disease. 2022. 8. 1. 97-97
Kensuke Daida, Shotaro Shimonaka, Kahori Shiba-Fukushima, Jun Ogata, Hiroyo Yoshino, Ayami Okuzumi, Taku Hatano, Yumiko Motoi, Tomoki Hirunagi, Masahisa Katsuno, et al. α-Synuclein V15A Variant in Familial Parkinson's Disease Exhibits a Weaker Lipid-Binding Property. Movement disorders : official journal of the Movement Disorder Society. 2022. 37. 10. 2075-2085
Jun-Yi Liu, Tsuyoshi Inoshita, Kahori Shiba-Fukushima, Shigeharu Yoshida, Kosuke Ogata, Yasushi Ishihama, Yuzuru Imai, Nobutaka Hattori. Ubiquitination at the lysine 27 residue of the parkin ubiquitin-like domain is suggestive of a new mechanism of parkin activation. Human molecular genetics. 2022. 31. 15. 2623-2638
Kahori Shiba-Fukushima, Yuzuru Imai. Monitoring PINK1-Parkin Signaling Using Dopaminergic Neurons from iPS Cells. Methods in molecular biology (Clifton, N.J.). 2021. 2322. 81-92

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MISC (32)：

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Professional career (1)：

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