Saito Yuki

サイトウユウキ | Saito Yuki

Affiliation and department：

Research field (5)： Nutrition and health science , Sports science , Orthopedics , Rehabilitation science , Anatomy

Research keywords (10)：骨格筋 , 関節リウマチ , 自己免疫疾患 , バイオインフォマティクス , Senescence , 間葉系幹細胞 , Chronic Inflammation , Fibrosis , Regenerative medicine , Rehabilitation

Research theme for competitive and other funds (11)：

2024 - 2027 運動誘発性細胞老化を基軸とした臓器間コミュニケーションと組織適応・修復機構の解明
2024 - 2027 老化細胞の運命決定機構から解明する関節リウマチ病態メカニズムと関節再生戦略
2023 - 2026 老化起源細胞から解明するHealthy agingと加齢性疾患の分岐点
2022 - 2025 老化細胞のメカノバイオロジー: メカニカルストレスによる細胞老化制御への挑戦
2022 - 2025 2022年度医学系研究助成

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Papers (25)：

Yuki Saito, Sena Yamamoto, Takako S. Chikenji. Role of cellular senescence in inflammation and regeneration. Inflammation and Regeneration. 2024. 44. 1
Arisa Kita, Sena Yamamoto, Yuki Saito, Takako S. Chikenji. Cellular senescence and wound healing in aged and diabetic skin. Frontiers in Physiology. 2024. 15
Shogo Ijima, Yuki Saito, Sena Yamamoto, Kentaro Nagaoka, Taiki Iwamoto, Arisa Kita, Maki Miyajima, Tsukasa Sato, Akihiro Miyazaki, Takako S Chikenji. Senescence-associated secretory phenotypes in mesenchymal cells contribute to cytotoxic immune response in oral lichen planus. Immunity & ageing : I & A. 2023. 20. 1. 72-72
Yuki Saito, Maki Miyajima, Sena Yamamoto, Norihiro Miura, Tsukasa Sato, Arisa Kita, Shogo Ijima, Mineko Fujimiya, Takako S Chikenji. Intrathecal Injection of Mesenchymal Stromal Cell Cultured on 3D Fiber Ameliorates Multiple Organ Damage in Murine Lupus. Stem Cells Translational Medicine. 2022
Arisa Kita, Yuki Saito, Norihiro Miura, Maki Miyajima, Sena Yamamoto, Tsukasa Sato, Takatoshi Yotsuyanagi, Mineko Fujimiya, Takako S Chikenji. Altered regulation of mesenchymal cell senescence in adipose tissue promotes pathological changes associated with diabetic wound healing. Communications biology. 2022. 5. 1. 310-310

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MISC (43)：

千見寺貴子, 齋藤悠城. 【老化を標的とした疾患予防・治療】老化細胞の光と影. 医学のあゆみ. 2023. 287. 5. 321-326
齋藤悠城, 千見寺貴子. 骨格筋の再生と細胞老化. 基礎理学療法学. 2022. 25. 1. 61-68
千見寺貴子, 齋藤悠城. 骨格筋における細胞老化と筋再生. 基礎老化研究. 2022. 46. 3. 8-8
檜森弘一, 芦田雪, 舘林大介, 齋藤悠城, 千見寺貴子, 山田崇史. 多発性筋炎に対する高強度伸張性収縮トレーニングの安全性と有効性の検討. 理学療法学. 2021. 47. Suppl.1. 124-124
Yuki Saito, Takako S. Chikenji. 運動による細胞老化制御と骨格筋再生. 2021. 40. 2. 86-91

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Lectures and oral presentations (26)：

Cellular Senescence in Epidermal Stem Cells as a Potential Driver of Lupus Erythematosus Skin Lesions
(ASCB|EMBO meeting Cell Bio 2023 2023)
Involvement of Cellular Senescence in the Pathogenesis of Lupus Nephritis in Mice
(ASCB|EMBO meeting Cell Bio 2023 2023)
Cellular senescence of synovial fibroblasts in rheumatoid arthritis model mice
(ASCB|EMBO meeting Cell Bio 2023 2023)
Exercise-induced senescence-like gene signature in fibro/adipogenic progenitors is impaired in diabetes muscle,
(ASCB|EMBO meeting Cell Bio 2023, , Minisymposia 2023)
Accumulation of senescent neurons in mice model of autism spectrum disorder with abnormal synaptic pruning.
(The 6th International Cell Senescence Association Conference 2021)

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Education (2)：

2014 - 2018 Sapporo Medical University Graduate School of Medicine
2012 - 2014 Sapporo Medical University Graduate School of Health Sciences

Professional career (2)：

修士 (理学療法学) (札幌医科大学)
博士 (医学) (札幌医科大学)

Work history (4)：

2021/06 - 現在 Sapporo Medical University
2019/09 - 2021/06 Sapporo Medical University School of Medicine, Department of Anatomy
2019/07 - 2019/08 Sapporo Medical University School of Medicine, Department of Anatomy
2018/06 - 2019/06 Mayo Clinic Department of Orthopedic Surgery,Tendon & Soft Tissue Biology Laboratory Post doctoral fellow

Awards (4)：

2023/12 - Cell Bio 2023, the joint meeting of the American Society for Cell Biology (ASCB) and European Molecular Biology Organization (EMBO) Top-scoring abstracts
2023/07 - Best Poster Award
2021/01 - Sapporo Medical University 札幌医科大学大学院医学研究科若手研究者最優秀論文賞
2020/02 - Orthopedic Research Society New Investigator Recognition Award (NIRA) Exercise enhances skeletal muscle regeneration by promoting senescence in fibro-adipogenic progenitors

Association Membership(s) (7)：

日本解剖学会 , International Cell Senescence Association , 日本炎症・再生医学会 , 日本再生医療学会 , Orthopedic Research Society , 日本臨床スポーツ医学会 , 日本理学療法士学会

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