Rchr
J-GLOBAL ID：202001013109918912   Update date: Oct. 22, 2024

Matsumoto Daisuke

マツモト ダイスケ | Matsumoto Daisuke
Affiliation and department：
Tokyo Metropolitan Institute of Medical Science Regenerative Medicine

About Tokyo Metropolitan Institute of Medical Science Regenerative Medicine


Research field  (2)： Chemical biology ,  Pharmaceuticals - chemistry and drug development
Research keywords  (2)： 遺伝子治療 ,  ゲノム編集
Research theme for competitive and other funds  (3)：
  • 2023 - 2025 Cas9を用いたゲノム編集におけるHDR効率向上に重要な要素の探索
  • 2021 - 2023 自律活性化型CRISPRを利用した正確なゲノム編集に必要な要素の探索
  • 2017 - 2019 RNAアプタマースイッチを利用した低オフターゲット効果ゲノム編集法の開発
Papers (15)：
  • Daisuke Matsumoto, Erina Matsugi, Kanae Kishi, Yuto Inoue, Kiyomi Nigorikawa, Wataru Nomura. SpCas9-HF1 enhances accuracy of cell cycle-dependent genome editing by increasing HDR efficiency, and by reducing off-target effects and indel rates. Molecular therapy. Nucleic acids. 2024. 35. 1. 102124-102124
  • Kiyomi Nigorikawa, Yu Fukushima, Chinatsu Shimada, Daisuke Matsumoto, Wataru Nomura. CRISPRa Analysis of Phosphoinositide Phosphatases Shows That TMEM55A Is a Positive Regulator of Autophagy. Biological & pharmaceutical bulletin. 2024. 47. 6. 1148-1153
  • Daisuke Matsumoto, Wataru Nomura. The history of genome editing: advances from the interface of chemistry & biology. Chemical communications (Cambridge, England). 2023. 59. 50. 7676-7684
  • Daisuke Matsumoto, Kanae Kishi, Erina Matsugi, Yuto Inoue, Kiyomi Nigorikawa, Wataru Nomura. Cas9-Geminin and Cdt1-fused anti-CRISPR protein synergistically increase editing accuracy. FEBS letters. 2023. 597. 7. 985-994
  • Daisuke Matsumoto, Wataru Nomura. Molecular Switch Engineering for Precise Genome Editing. Bioconjugate Chemistry. 2021. 32. 4. 639-648
ｍore...
MISC (26)：
  • 松木依理奈, 岸彩音, 松本大亮, 松本大亮, 濁川清美, 濁川清美, 野村渉, 野村渉. Cell cycle-dependent genome editing utilizing SauCas9 and AAV delivery. 日本薬学会年会要旨集(Web). 2024. 144th
  • 岸果苗, 濁川清美, 濁川清美, 松本大亮, 松本大亮, 野村渉, 野村渉. A cell cycle-dependent CRISPR activation system regulated by anti-CRISPR and its analysis in living cells. 日本薬学会年会要旨集(Web). 2024. 144th
  • 松本大亮. Cell cycle-dependent CRISPR activation system for high-precision genome editing. 日本薬学会年会要旨集(Web). 2024. 144th
  • 松木依理奈, 岸彩音, 松本大亮, 松本大亮, 濁川清美, 濁川清美, 野村渉, 野村渉. 相同組み換え修復効率の向上を志向したSauCas9による細胞周期依存型ゲノム編集. 日本生化学会大会(Web). 2023. 96th
  • 岸果苗, 濁川清美, 濁川清美, 長谷川有希, 松本大亮, 松本大亮, 野村渉, 野村渉. Analysis of Cas9 inhibition mechanism of anti-CRISPR in cells by using CRISPRa system. 日本化学会春季年会講演予稿集(Web). 2023. 103rd
ｍore...
Patents (2)：
Books (2)：
  • ナノニードルアレイを用いたメカノポレーションによる生細胞への分子導入
    公益社団法人日本生物工学会 2018
  • 化学
    2016
Education (3)：
  • 2016 - 2019 Tokyo Medical and Dental University Graduate School of Medical and Dental Sciences Track of Life Science and Technology
  • 2014 - 2016 Tokyo University of Agriculture and Technology Graduate School of Engineering Department of Biotechnology and Life Science
  • 2010 - 2014 Tokyo University of Agriculture and Technology Faculty of Engineering Department of Biotechnology and Life Science
Professional career (1)：
  • 博士(理学) (東京医科歯科大学)
Work history (6)：
  • 2024/09 - 現在 Tokyo Metropolitan Institute of Medical Science Regenerative Medicine
  • 2020/10 - 2024/08 Hiroshima University
  • 2019/04 - 2020/09 スクリプス研究所
  • 2017/04 - 2019/03 Japan Society for the Promotion of Science
  • 2016/04 - 2017/03 Tokyo Medical and Dental University Graduate School of Medical and Dental Sciences Track of Medical and Dental Science and Technology
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Awards (7)：
  • 2019/02 - 東洋紡バイオテクノロジー研究財団 平成30年度長期研究助成(留学、招聘)
  • 2019/01 - 17th IBB BioFuture Research Encouragement Prize 大学院博士課程の部最優秀賞
  • 2017/09 - 第69回日本生物工学会大会 第25回生物工学論文賞
  • 2017/01 - 15th IBB BioFuture Research Encouragement Prize 大学院博士課程の部優秀賞
  • 2016/07 - 創薬懇話会 2016 in 蓼科 ベストディスカッション賞
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