Rchr
J-GLOBAL ID：202001013219684674
Update date: May. 18, 2024
Uruno Takehito
ウルノ タケヒト | Uruno Takehito
Affiliation and department：
Job title：
准教授
Research field (2)：
Medical biochemistry
, Functional biochemistry
Research keywords (3)：
Metabolites, bioactive substances
, Immune control of disease
, Biochemistry
Research theme for competitive and other funds (2)：
- 2019 - 2022 Analyses for expression and function of the sulfotransferase SULT2B1b
- 2019 - 2021 RAS変異を有する難治性がんの新規分子標的治療薬の非臨床評価
Papers (43)：
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宇留野 武人, 竜口 崇明, 杉浦 悠毅, 福井 宣規. がん免疫療法に対する抵抗性を付与する腫瘍メタボライト. 日本がん免疫学会総会プログラム・抄録集. 2023. 27回. 173-173
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Kazufumi Kunimura, Sayaka Akiyoshi, Takehito Uruno, Keisuke Matsubara, Daiji Sakata, Kenji Morino, Kenichiro Hirotani, Yoshinori Fukui. DOCK2 regulates MRGPRX2/B2-mediated mast cell degranulation and drug-induced anaphylaxis. Journal of Allergy and Clinical Immunology. 2023. 151. 6. 1585-1594.e9
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Kenji Morino, Kazufumi Kunimura, Yuki Sugiura, Yoshihiro Izumi, Keisuke Matsubara, Sayaka Akiyoshi, Rae Maeda, Kenichiro Hirotani, Daiji Sakata, Seiya Mizuno, et al. Cholesterol sulfate limits neutrophil recruitment and gut inflammation during mucosal injury. Frontiers in immunology. 2023. 14. 1131146-1131146
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國村 和史, 宇留野 武人, 杉浦 悠毅, 福井 宣規. コレステロール関連代謝産物と疾患制御 コレステロール硫酸は白血球の遊走制御を介して眼の免疫特権環境の形成に寄与する. 日本生化学会大会プログラム・講演要旨集. 2022. 95回. 2S01e-04
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Kazufumi Kunimura, Kazuhiko Yamamura, Takeshi Nakahara, Makiko Kido-Nakahara, Takehito Uruno, Yoshinori Fukui. Identification of a functional DOCK8 gene polymorphism associated with atopic dermatitis. Allergy. 2022. 77. 12. 3670-3672
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Lectures and oral presentations (2)：
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A tumor metabolite impacting immunotherapy efficacy: Cholesterol sulfate regulates tumor-immune interactions
(Keystone Symposia "Cancer Immunotherapy: Mechanisms of Response versus Resistance" 2023)
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DOCK1 as a novel molecular target for controlling cancer cell survival and invasion
(25th Biennial Congress on the European Association for Cancer Research 2018)
Professional career (1)：
Awards (1)：
- 2017/09 - 公益財団法人 内藤記念科学振興財団 内藤記念科学奨励金・研究助成
Association Membership(s) (3)：
日本がん免疫学会
, 日本生理学会
, The Japanese Biochemical Society
