Research theme for competitive and other funds (7)：
2023 - 2027 口腔がんの転移をもたらすリンパ節線維芽細胞様細網細胞の変異メカニズムの解明
2021 - 2023 糖尿病誘発因子を標的とした新規骨破壊制御法の開発に関する研究
2018 - 2021 Osteoblast-specific cell-surface antigen regulating recruitment of osteoclasts: Bone regeneration based on the new concept concerning the regulation of bone remodeling
2019 - 2020 Regulation of pathological bone destruction targeting membrane molecules expressed in pathologically activated osteoclasts
2015 - 2018 Roles of bone metastatic mammary tumor cell-derived extracellular vesicles in osteoclast differentiation and function
2016 - 2017 Interaction between bone and adipose tissue and control of obesity and glucose metabolism through the secretion factors derived from osteoclasts
2014 - 2015 Control of bone destruction by RBP4, an inducible factor of diabetes
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Papers (38)：
Sara Murata, Soichiro Sonoda, Yukari Kyumoto-Nakamura, M. Majd Sharifa, Liting Yu, Reona Aijima, Erika Yamauchi-Tomoda, Fouad MHD. Zakaria, Hiroki Kato, Norihisa Uehara, et al. Deciduous pulp stem cell-derived extracellular vesicles stimulate the proliferation of cartilage progenitor cells via extracellular signal-regulated protein kinase 1/2 activation. Scientific Reports. 2026
Soichiro Sonoda, Liting Yu, Lisha Dai, Yukari Kyumoto-Nakamura, Koichiro Yoshimaru, Ratih Yuniartha, Ying Liu, M Majd Sharifa, Sara Murata, Mohammed Fouad Zakaria, et al. Dental pulp stem cells maintain epigenetic chromatin architecture remodeling primed by the etiological stimulus of biliary atresia. Stem cell research & therapy. 2026
Mohammed Fouad Zakaria, Hiroki Kato, Soichiro Sonoda, Kenichi Kato, Norihisa Uehara, Yukari Kyumoto-Nakamura, Mohammed Majd Sharifa, Liting Yu, Lisha Dai, Haruyoshi Yamaza, et al. NaV1.1 contributes to the cell cycle of human mesenchymal stem cells by regulating AKT and CDK2. Journal of Cell Science. 2024
Mhd Fouad Zakaria, Soichiro Sonoda, Hiroki Kato, Lan Ma, Norihisa Uehara, Yukari Kyumoto-Nakamura, M Majd Sharifa, Liting Yu, Lisha Dai, Erika Yamauchi-Tomoda, et al. Erythropoietin receptor signal is crucial for periodontal ligament stem cell-based tissue reconstruction in periodontal disease. Scientific reports. 2024. 14. 1. 6719-6719
Tamer Badawy, 久本 由香里, 上原 範久, 張 旌旗, 山座 孝義, 久木田 明子, 久木田 敏夫. 破骨細胞形成と石灰化を調節する骨芽細胞系特異的細胞表面抗原 骨リモデリングに関与する可能性のある新規プレイヤー(Osteoblast lineage-specific cell-surface antigen regulating osteoclastogenesis and calcification: A possible new player in bone remodeling). Journal of Oral Biosciences Supplement. 2018. 2018. 175-175
Osteoclasts Formed under Stimulation by IL-1β Possess Extremely High Ability to Secrete Protons and to Resorb Dentin with Abnormal Adhesiveness, Imaged by pH-Sensitive Fluorescence Probes
(American Society for Bone and Mineral Research 2017 Annual Meeting 2017)
The Japanese Association of Anatomists
, The Japanese Society for Bone and Mineral Research
, The Japanese Pharmacological Society
, Japanese Association for Oral Biiology
