Higashide Mika

Research field (2)： Genetics , Molecular biology

Research keywords (3)： CRISPR/Cas13 , Genome editing , meiotic recombination

Research theme for competitive and other funds (2)：

Papers (10)：

Jeong H Joo, Soogil Hong, Mika T Higashide, Eui-Hwan Choi, Seobin Yoon, Min-Su Lee, Hyun Ah Kang, Akira Shinohara, Nancy Kleckner, Keun P Kim. RPA interacts with Rad52 to promote meiotic crossover and noncrossover recombination. Nucleic Acids Research. 2024
Kyoka Kajii, Ayu Shimomura, Mika T. Higashide, Masaya Oki, Gakushi Tsuji. Effects of Sugars on Giant Unilamellar Vesicle Preparation, Fusion, PCR in Liposomes, and Pore Formation. Langmuir. 2022
Lee MS, Higashide MT, Choi H, Li K, Hong S, Lee K, Shinohara A, Shinohara M, Keun P Kim. The synaptonemal complex central region modulates crossover pathways and feedback control of meiotic double-strand break formation. Nucleic acids research. 2021. 49. 13. 7537-7553
Srinivas Bandaru, Mika Higashide Tsuji, Yurika Shimizu, Kaya Usami, Suni Lee, Naoko Kumagai Takei, Kei Yoshitome, Yasumitsu Nishimura, Takemi Otsuki, Tatsuo Ito. Structure-based design of gRNA for Cas13. Scientific reports. 2020. 10. 1. 11610-11610
Tai-Ting Woo, Chi-Ning Chuang, Mika Higashide, Akira Shinohara, Ting-Fang Wang. Dual roles of yeast Rad51 N-terminal domain in repairing DNA double-strand breaks. Nucleic acids research. 2020. 48. 15. 8474-8489

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MISC (7)：

篠原美紀, 篠原美紀, 篠原美紀, 東出望花, 東出望花, 東出望花, 李珂, 李珂, 李珂. シナプトネマ複合体の中央領域は減数分裂期交差型組換え形成とDSB形成フィードバック制御に機能する. 日本分子生物学会年会プログラム・要旨集(Web). 2020. 43rd
Mika Higashide, Miki Shinohara. Slx4, multifunctional scaffold protein, functions for negative regulation of CO formation specific in centromere-proximal region and DSB distribution on entire chromosomes. GENES & GENETIC SYSTEMS. 2016. 91. 6. 355-355
篠原美紀, 岩崎大地, 林原加代子, 東出望花, 寺澤匡博, Gasse Susan M. 酵母Xrs2のFHAドメインはATM/Tel1の活性維持とKuのDSB単鎖末端からの解離に必要である. 日本放射線影響学会大会講演要旨集. 2016. 59回. 24-24
Mika Higashide, Miki Shinohara. Elongation of synaptonemal complex in meiosis regulates crossover numbers between homologs dependent on chromosome-size. GENES & GENETIC SYSTEMS. 2015. 90. 6. 389-389
Mika Higashide, Miki Shinohara. Gmc2, a novel synaptonemal complex component, regulates the number of crossovers between homologous chromosomes in meiosis. GENES & GENETIC SYSTEMS. 2014. 89. 6. 324-324

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Education (3)：

2013 - 2017 Osaka University Graduate School of Science Department of Biological Sciences
2011 - 2013 Osaka University Graduate School of Science Department of Biological Sciences
2007 - 2011 Nara Women's University Faculty of Science Department of Biological Science

Work history (4)：

2023/04 - 現在 University of Fukui Faculty of Engineering JSPS Research Fellowship for Young Scientists (RPD)
2020/04 - 現在 University of Fukui Faculty of Engineering
2018/04 - 2020/03 Osaka University Institute for Protein Research Assistant professor
2017/04 - 2018/03 Okayama University Graduate School of Medicine , Dentistry and Pharmaceutical Sciences Part-time researcher

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