Rchr
J-GLOBAL ID：202001014845578530
Update date: Feb. 28, 2023
Hiramatsu Naoki
ヒラマツ ナオキ | Hiramatsu Naoki
Affiliation and department：
Job title：
副院長 兼 消化器内科部長
Research field (1)：
Gastroenterology
Research keywords (1)：
ウイルス肝炎・肝硬変、肝細胞癌、発症機序、診断と治療
Research theme for competitive and other funds (18)：
- 2013 - 2016 The relationship between the efficacy and the prevalence of the mutant virus for the novel anti-viral drugs for hepatitis C
- 2010 - 2012 Development of novel therapy for hepatocellular carcinoma targeting of bone marrow-derived angiogenesis precursor
- 2010 - 2012 Investigation for the mechanisms of immune tolerance against HCV mediated by tryptophan-catalyzing enzyme, IDO
- 2008 - 2010 Analysis of NASH pathophysiology using glycobiological technique
- 2007 - 2009 Developmental research of tailored immune-modulation therapy against refractory chronic hepatitis C.
- 2007 - 2009 Developmental research on dendritic cell-based immunotherapy against chronic hepatitis C and hepatocellular carcinoma
- 2006 - 2007 Molecular regulation of NK cell cytotoxicity fir human hepatocellular carcinoma
- 2006 - 2007 Hepatitis B virus mutations affecting synthesis of relaxed-circular viral DNA : Relation to disease severity
- 2003 - 2007 Regulation of dendritic cell function and cell-based therapy in chronic hepatitis C virus infection
- 2005 - 2006 CTL immuno-monitoring in chronic hepatitis C
- 2005 - 2006 HBV遺伝子導入マウスでの酵素阻害剤誘発変異の解析とテーラーメイド医療への応用
- 2004 - 2006 Establishment of plasmacytoid dendritic cell-based immune therapy against viral hepatitis and hepatocellular carcinoma
- 2002 - 2003 Suppression of hepatocarcinogenesis by activating natural killer T cells
- 2000 - 2001 Therapeutic strategy for hepatocellular carcinoma by dendritic cell-based tumor vaccination
- 1999 - 2000 Therapetic strategy for chronic hepatitis C by inducing apoptosis of hepatocyte infected with hepatitis C virus
- 1999 - 2000 Application of Ninjurin, a novel adhesion molecule, to diagnosis and therapeutics of primary hepatocellular carcinoma
- 1998 - 2000 Analysis of the molecular mechanism of hepatocarcinogenesis in patients with chronic viral diseases and its application for genetic diagnosis of hepatocellular carcinoma.
- 1996 - 1998 Therapeutic approach to hepatitis C using single-chain antibody and DNA gene transfer
Show all
Papers (278)：
-
Yuki Tahata, Ryotaro Sakamori, Ryoko Yamada, Takahiro Kodama, Hayato Hikita, Yasutoshi Nozaki, Masahide Oshita, Naoki Hiramatsu, Masanori Miyazaki, Eiji Mita, et al. Risk of hepatocellular carcinoma after sustained virologic response in hepatitis C virus patients without advanced liver fibrosis. Hepatology research : the official journal of the Japan Society of Hepatology. 2022. 52. 10. 824-832
-
Hideki Hagiwara, Yoshiki Ito, Takashi Ohta, Yasutoshi Nozaki, Takayuki Iwamoto, Atsushi Hosui, Naoki Hiramatsu, Yuki Tahata, Ryotaro Sakamori, Hayato Hikita, et al. Incidence and risk factors of hepatocellular carcinoma in patients with hepatitis C who achieved a sustained virological response through direct-acting antiviral agents among the working population in Japan. JGH open : an open access journal of gastroenterology and hepatology. 2022. 6. 6. 395-401
-
Atsuo Takigawa, Ryotaro Sakamori, Yuki Tahata, Teppei Yoshioka, Ryoko Yamada, Takahiro Kodama, Hayato Hikita, Takayuki Yakushijin, Kazuyoshi Ohkawa, Naoki Hiramatsu, et al. Prediction Model for Intrahepatic Distant Recurrence After Radiofrequency Ablation for Primary Hepatocellular Carcinoma 2 cm or Smaller. Digestive diseases and sciences. 2022. 67. 12. 5704-5711
-
Yuta Myojin, Hayato Hikita, Yuki Tahata, Akira Doi, Seiya Kato, Yoichi Sasaki, Kumiko Shirai, Sadatsugu Sakane, Ryoko Yamada, Takahiro Kodama, et al. Serum growth differentiation factor 15 predicts hepatocellular carcinoma occurrence after hepatitis C virus elimination. Alimentary pharmacology & therapeutics. 2022. 55. 4. 422-433
-
Kazuki Maesaka, Ryotaro Sakamori, Ryoko Yamada, Yuki Tahata, Masahide Oshita, Hideki Hagiwara, Mitsuru Sakakibara, Shinji Tamura, Naoki Hiramatsu, Masami Inada, et al. Clinical course of hepatitis C virus-positive patients with decompensated liver cirrhosis in the era of direct-acting antiviral treatment. Hepatology research : the official journal of the Japan Society of Hepatology. 2021. 51. 5. 517-527
ｍore...
MISC (83)：
-
Ayako Urabe, Ryotaro Sakamori, Tomohide Tatsumi, Takayuki Yakushijin, Ryoko Yamada, Tsugiko Oze, Naoki Morishita, Yuki Tahata, Atsushi Hosui, Takuya Miyagi, et al. Efficacy and safety of sofosbuvir-based therapy for aged patients with chronic hepatitis C. HEPATOLOGY. 2016. 64. 996A-997A
-
西尾啓, 巽智秀, 須田貴広, 大西良輝, 末村茂樹, 瀧川貴生, 氣賀澤斉史, 吉岡鉄平, 俵誠一, 青野悟志, et al. C型慢性肝炎における肝細胞アポトーシス亢進はCD14陽性細胞由来のGalectin-9の産生を誘導する. 肝臓. 2016. 57. Suppl.1. A273-A273
-
甲斐優吾, 疋田隼人, 巽智秀, 坂根貞嗣, 塩出悠登, 村井一裕, 野崎泰俊, 牧野祐紀, 中堀輔, 齋藤義修, et al. ヒト肝細胞キメラマウスを用いたDAA治療誘導性変異型HCVに対するDAA再治療に関する検討. 肝臓. 2016. 57. Suppl.1. A276-A276
-
Yuki Tahata, Naoki Hiramatsu, Tsugiko Oze, Ayako Urabe, Naoki Morishita, Ryoko Yamada, Takayuki Yakushijin, Yukiko Saji, Yoshinori Doi, Hideki Hagiwara, et al. High ribavirin dose and extended treatment can raise sustained virologic response in chronic hepatitis C genotype 1 patients treated with simeprevir, pegylated interferon plus ribavirin. HEPATOLOGY. 2015. 62. 804A-804A
-
Ayako Urabe, Naoki Hiramatsu, Tsugiko Oze, Takayuki Yakushijin, Ryoko Yamada, Naoki Morishita, Yuki Tahata, Yuichi Yoshida, Tomohide Tatsumi, Masahide Oshita, et al. Risk factors for progression of liver disease status in Japanese patients with non-alcoholic steatohepatitis. HEPATOLOGY. 2015. 62. 1286A-1287A
ｍore...
Books (3)：
-
肝炎どう診る?どう治す?
医事新報社 2020
-
はじめての消化器内視鏡看護
メディカ出版 2019 ISBN:9784840469258
-
必ず役立つ!肝炎診療バイブル : 研修医・レジデント必携 : 各種ガイドライン準拠 = The bible of treatment for hepatitis
メディカ出版 2018 ISBN:9784840465267
Education (1)：
Association Membership(s) (1)：
日本肝臓学会、日本消化器病学会、日本内視鏡学会、日本膵臓学会、米国肝臓学会、欧州肝臓学会
