Koike (Ouchi) Rie

コイケリエ | Koike (Ouchi) Rie

Affiliation and department：
Other affiliations (1)：

National Museum of Emerging Science and Innovation(MIRAIKAN) Human Organoid Project

Research field (2)： Cell biology , Molecular biology

Research keywords (3)：非アルコール性脂肪性肝炎(NASH) , Autonomic nerves , Organoid

Research theme for competitive and other funds (2)：

Papers (10)：

Hiroyuki Koike, Kentaro Iwasawa, Rie Ouchi, Mari Maezawa, Masaki Kimura, Asuka Kodaka, Shozo Nishii, Wendy L Thompson, Takanori Takebe. Engineering human hepato-biliary-pancreatic organoids from pluripotent stem cells. Nature protocols. 2021
Tadahiro Shinozawa, Masaki Kimura, Yuqi Cai, Norikazu Saiki, Yosuke Yoneyama, Rie Ouchi, Hiroyuki Koike, Mari Maezawa, Ran-Ran Zhang, Andrew Dunn, et al. High-Fidelity Drug-Induced Liver Injury Screen Using Human Pluripotent Stem Cell-Derived Organoids. Gastroenterology. 2020
Naritaka Kobayashi, Shodai Togo, Takahisa Matsuzaki, Kaede Hashiseko, Ryuzo Kawamura, Masami Suganuma, Seiichiro Nakabayashi, Yosuke Yoneyama, Rie Ouchi, Takanori Takebe, et al. Stiffness distribution analysis in indentation depth direction reveals clear mechanical features of cells and organoids by using AFM. Applied Physics Express. 2020. 13. 9
Hiroyuki Koike, Kentaro Iwasawa, Rie Ouchi, Mari Maezawa, Kirsten Giesbrecht, Norikazu Saiki, Autumn Ferguson, Masaki Kimura, Wendy L Thompson, James M Wells, et al. Modelling human hepato-biliary-pancreatic organogenesis from the foregut-midgut boundary. Nature. 2019. 574. 7776. 112-116
Rie Ouchi, Shodai Togo, Masaki Kimura, Tadahiro Shinozawa, Masaru Koido, Hiroyuki Koike, Wendy Thompson, Rebekah A Karns, Christopher N Mayhew, Patrick S McGrath, et al. Modeling Steatohepatitis in Humans with Pluripotent Stem Cell-Derived Organoids. Cell metabolism. 2019. 30. 2. 374-384

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MISC (7)：

小池梨江. 多細胞系からなるヒト肝臓オルガノイドを用いたNAFLDの病態モデルの再現. 日本再生医療学会総会(Web). 2021. 20th
大内梨江, 武部貴則. 【iPS再生医療の最前線】iPS細胞を用いたヒューマン・オルガノイド研究. BIO Clinica. 2019. 34. 13. 1306-1310
藤友崇, 大井潤, 大内梨江, 米山鷹介, 吉澤絵美, 武部貴則, 武部貴則, 武部貴則. 「MYCODE Research」を活用したゲノム層別化iPS細胞研究. 日本再生医療学会総会(Web). 2019. 18th
東郷祥大, 東郷祥大, 大内梨江, 篠澤忠紘, 小池博之, 吉川洋史, 武部貴則. ヒトiPS細胞由来肝臓オルガノイドを用いた炎症・線維化モデルの構築. 応用物理学会春季学術講演会講演予稿集(CD-ROM). 2018. 65th
東郷祥大, 東郷祥大, 大内梨江, 篠澤忠紘, 小池博之, 吉川洋史, 武部貴則. ヒトiPS細胞由来肝臓オルガノイドを用いた炎症・線維化モデルの構築. 応用物理学会秋季学術講演会講演予稿集(CD-ROM). 2017. 78th

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Patents (1)：

Books (1)：

Lectures and oral presentations (23)：

Modeling Steatohepatitis with Multicellular Organoids from Human Induced Pluripotent Stem Cells
(The International Society for Stem Cell Research (ISSCR) 2021 2021)
Modeling NAFLD with Multicellular Liver Organoid from Human Pluripotent Stem Cell
(The 20th Congress of the Japanese Society for Regenerative Medicine 2021)
炎症・線維化病態を再現するヒューマンオルガノイド技術の開発の成功
(United Japanese Researchers Around the World Paper Award 2020 2020)
「MYCODE Research」を活用したゲノム層別化iPS細胞研究
(The 18th Congress of the Japanese Society for Regenerative Medicine 2019)
ヒトiPS細胞由来肝臓オルガノイドを用いた炎症・線維化モデルの構築
(第65回応用物理学会春季学術講演会 2018)

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Education (4)：

2013 - 2016 The University of Tokyo Department of Computational Biology and Medical Sciences
2011 - 2013 Yokohama City University
2009 - 2011 Tamagawa University Department of Life Science
2006 - 2008 College of the Desert

Work history (4)：

2018/06 - 現在 Tokyo Medical and Dental University Institute of Research, Division of Advanced Multidisciplinary Research, Organ and Tissue Neogenesis Consortium
2016/06 - 2018/06 Cincinnati Children’s Hospital Medical Center Division of Developmental Biology, Division of Gastroenterology, Hepatology and Nutrition Research Fellow
2016/04 - 2016/06 Japanese Foundation for Cancer Research The Cancer Chemotherapy Center, Molecular Biotherapy
2014/04 - 2016/03 Japan Society for the Promotion of Science Research Fellow

Awards (16)：

2021/10 - Astellas Foundation for Research on Metabolic Disorders Takenaka Incentive Award
2020/10 - United Japanese researchers Around the world (UJA) United Japanese researchers Around the world (UJA) Outstanding Paper Award Modeling Steatohepatitis in Humans with Pluripotent Stem Cell-Derived Organoids
2020 - Corning 2020 Corning Life Science Ambassador
2019/09 - Tokyo Medical and Dental University The Third Generation Researcher Training Unit
2017/02 - Cincinnati Children's Hospital Medical Center Third Place at the Poster Presentation in Digestive Health Center Annual Scientific Retreat,

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