Rchr
J-GLOBAL ID:202001015186630410   Update date: Jun. 20, 2024

Ouchi Rie

オオウチ リエ | Ouchi Rie
Affiliation and department:
Research field  (2): Cell biology ,  Molecular biology
Research keywords  (5): Aging ,  Senescence ,  Rejuvenation ,  Organoid ,  Autonomic nerve
Research theme for competitive and other funds  (2):
  • 2021 - 2023 ヒト肝臓オルガノイドを用いた肝内自律神経によるNASHの病態進展制御機構の解明
  • 2014 - 2016 グリオブラストーマ幹細胞におけるテロメア長維持機構の解明
Papers (11):
  • Rie Ouchi, Hiroyuki Koike. Modeling human liver organ development and diseases with pluripotent stem cell-derived organoids. Frontiers in Cell and Developmental Biology. 2023. 11
  • Hiroyuki Koike, Kentaro Iwasawa, Rie Ouchi, Mari Maezawa, Masaki Kimura, Asuka Kodaka, Shozo Nishii, Wendy L Thompson, Takanori Takebe. Engineering human hepato-biliary-pancreatic organoids from pluripotent stem cells. Nature protocols. 2021. 16. 2. 919-936
  • Tadahiro Shinozawa, Masaki Kimura, Yuqi Cai, Norikazu Saiki, Yosuke Yoneyama, Rie Ouchi, Hiroyuki Koike, Mari Maezawa, Ran-Ran Zhang, Andrew Dunn, et al. High-Fidelity Drug-Induced Liver Injury Screen Using Human Pluripotent Stem Cell-Derived Organoids. Gastroenterology. 2020. 160. 3. 831-846
  • Naritaka Kobayashi, Shodai Togo, Takahisa Matsuzaki, Kaede Hashiseko, Ryuzo Kawamura, Masami Suganuma, Seiichiro Nakabayashi, Yosuke Yoneyama, Rie Ouchi, Takanori Takebe, et al. Stiffness distribution analysis in indentation depth direction reveals clear mechanical features of cells and organoids by using AFM. Applied Physics Express. 2020. 13. 9
  • Hiroyuki Koike, Kentaro Iwasawa, Rie Ouchi, Mari Maezawa, Kirsten Giesbrecht, Norikazu Saiki, Autumn Ferguson, Masaki Kimura, Wendy L Thompson, James M Wells, et al. Modelling human hepato-biliary-pancreatic organogenesis from the foregut-midgut boundary. Nature. 2019. 574. 7776. 112-116
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MISC (8):
  • 小池梨江. 多細胞系からなるヒト肝臓オルガノイドを用いたNAFLDの病態モデルの再現. 日本再生医療学会総会(Web). 2021. 20th
  • 大内 梨江, 武部 貴則. 【iPS再生医療の最前線】iPS細胞を用いたヒューマン・オルガノイド研究. BIO Clinica. 2019. 34. 13. 1306-1310
  • 藤友崇, 大井潤, 大内梨江, 米山鷹介, 吉澤絵美, 武部貴則, 武部貴則, 武部貴則. 「MYCODE Research」を活用したゲノム層別化iPS細胞研究. 日本再生医療学会総会(Web). 2019. 18th
  • 東郷祥大, 東郷祥大, 大内梨江, 篠澤忠紘, 小池博之, 吉川洋史, 武部貴則. ヒトiPS細胞由来肝臓オルガノイドを用いた炎症・線維化モデルの構築. 応用物理学会春季学術講演会講演予稿集(CD-ROM). 2018. 65th
  • 東郷祥大, 東郷祥大, 大内梨江, 篠澤忠紘, 小池博之, 吉川洋史, 武部貴則. ヒトiPS細胞由来肝臓オルガノイドを用いた炎症・線維化モデルの構築. 応用物理学会秋季学術講演会講演予稿集(CD-ROM). 2017. 78th
more...
Patents (1):
Books (1):
  • オルガノイド実験スタンダード : 決定版 : 開発者直伝!珠玉のプロトコール集
    羊土社 2019 ISBN:9784758122399
Lectures and oral presentations  (27):
  • もっとくわしく #みんなの肝臓リサーチ第2弾
    (日本科学未来館主催イベント (一般公開) 2023)
  • 多細胞系ヒト肝臓オルガノイドを用いたNASHの制御機構の解明
    (アステラス病態研究会 第52回オンライン研究報告会「竹中奨励賞受賞講演」 2022)
  • もっとくわしく #みんなの肝臓リサーチ
    (日本科学未来館主催イベント (一般公開) 2022)
  • どうする? みんなの肝臓リサーチ
    (日本科学未来館主催イベント (一般公開) 2022)
  • Modeling Steatohepatitis with Multicellular Organoids from Human Induced Pluripotent Stem Cells
    (The International Society for Stem Cell Research (ISSCR) 2021 2021)
more...
Education (4):
  • 2013 - 2016 The University of Tokyo Graduate School of Frontier Sciences Department of Computational Biology and Medical Sciences
  • 2011 - 2013 Yokohama City University Graduate School of Medicine
  • 2009 - 2011 Tamagawa University College of Agriculture Department of Life Science
  • 2006 - 2008 College of the Desert
Professional career (1):
  • PhD (The University of Tokyo)
Work history (6):
  • 2024/02 - 現在 Tokyo Medical and Dental University Graduate School of Medical and Dental Sciences
  • 2021/04 - 2024/01 日本科学未来館 ヒューマンオルガノイドプロジェクト プロジェクトサブリーダー(兼任)
  • 2018/06 - 2024/01 Tokyo Medical and Dental University Institute of Research, Division of Advanced Multidisciplinary Research, Organ and Tissue Neogenesis Consortium
  • 2016/06 - 2018/06 Cincinnati Children’s Hospital Medical Center Division of Developmental Biology, Division of Gastroenterology, Hepatology and Nutrition Research Fellow
  • 2016/04 - 2016/06 Japanese Foundation for Cancer Research The Cancer Chemotherapy Center, Molecular Biotherapy
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Awards (16):
  • 2021/10 - Astellas Foundation for Research on Metabolic Disorders Takenaka Incentive Award
  • 2020/10 - United Japanese researchers Around the world (UJA) United Japanese researchers Around the world (UJA) Outstanding Paper Award Modeling Steatohepatitis in Humans with Pluripotent Stem Cell-Derived Organoids
  • 2020 - Corning 2020 Corning Life Science Ambassador
  • 2019/09 - Tokyo Medical and Dental University The Third Generation Researcher Training Unit
  • 2017/02 - Cincinnati Children's Hospital Medical Center Third Place at the Poster Presentation in Digestive Health Center Annual Scientific Retreat,
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