Rchr
J-GLOBAL ID:202001018638405655   Update date: Jul. 14, 2024

OISHI Atsuro

オオイシ アツロウ | OISHI Atsuro
Affiliation and department:
Job title: 講師
Research field  (4): Anatomy ,  Metabolism and endocrinology ,  Pharmacology ,  Cell biology
Research theme for competitive and other funds  (6):
  • 2022 - 2028 オーファンGPCRのリガンド発見と新たながん治療の創生
  • 2024 - 2027 血管内皮・間質組織における遺伝子変異細胞のモザイク率が血管奇形の病態に与える影響
  • 2022 - 2025 臨床検体を用いたDeorphanizationへの挑戦
  • 2022 - 2023 メタボリックGPRを標的とした新たな糖尿病・糖尿病性腎症への治療法の探求
  • 2022 - 2023 細胞が感じるフォースをリアルタイムに生きた細胞で定量化するプローブの開発
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Papers (20):
  • Gloria Somalo-Barranco, Antonio C Pagano Zottola, Abdulrasheed O Abdulrahman, Rami M El Zein, Astrid Cannich, Lourdes Muñoz, Carme Serra, Atsuro Oishi, Giovanni Marsicano, Bernard Masri, et al. Mitochondria-targeted melatonin photorelease supports the presence of melatonin MT1 receptors in mitochondria inhibiting respiration. Cell chemical biology. 2023. 30. 8. 920-932
  • Erika Cecon, Atsuro Oishi, Marine Luka, Delphine Ndiaye-Lobry, Arnaud François, Mathias Lescuyer, Fany Panayi, Julie Dam, Patricia Machado, Ralf Jockers. Novel repertoire of tau biosensors to monitor pathological tau transformation and seeding activity in living cells. eLife. 2023. 12
  • Atsuro Oishi, Ralf Jockers. Measuring Protein-Protein Interactions of Melatonin Receptors by Bioluminescence Resonance Energy Transfer (BRET). Methods in Molecular Biology. 2022. 2550. 207-218
  • Atsuro Oishi, Ralf Jockers. Recent Advances in Orphan GPCRs Research and Therapeutic Potential. GPCRs as Therapeutic Targets. 2022. 20-59
  • Manon Duquenne, Cintia Folgueira, Cyril Bourouh, Marion Millet, Anisia Silva, Jérôme Clasadonte, Monica Imbernon, Daniela Fernandois, Ines Martinez-Corral, Soumya Kusumakshi, et al. Leptin brain entry via a tanycytic LepR-EGFR shuttle controls lipid metabolism and pancreas function. Nature Metabolism. 2021
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MISC (1):
  • 大石 篤郎, 槙田 紀子. 東大病院内科研修医セミナー 16 悪性褐色細胞種の長期生存例. medicina. 2006. 43. 11. 1936-1941
Lectures and oral presentations  (9):
  • β-arrestin-2 conformational BRET biosensor monitoring tail and core conformation via GPCR-β-arrestin-2 interaction.
    (The 126th Annual Meeting of The Japanese Association of Anatomists 2021)
  • β-arrestin-2 conformational BRET biosensor monitoring tail and core conformation via GPCR-β-arrestin-2 interaction Annual meeting of GDR3545
    (Annual meeting of GDR3545 2020)
  • β-arrestin-2 BRET biosensors detect different β-arrestin-2 conformations in interaction with GPCRs.
    (Third ERNEST(European Research Network on Signal Transduction) meeting 2020)
  • Allosteric modulation of MT2 signaling by GPR61, GPR62 and GPR135, three orphan members of the melatonin receptor subfamily.
    (Annual meeting of GDR3545 Paris, France 2017)
  • 健常者でのフルマラソン中のCGMの検討
    (第616回日本内科学会関東地方会 2015)
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Education (3):
  • 2006 - 2012 東京大学大学院医学系研究科内科学専攻
  • 1999 - 2003 東京大学医学部医学科
  • 1997 - 1999 東京大学理科三類
Work history (5):
  • 2020/09 - 現在 杏林大学医学部 肉眼解剖学教室 講師
  • 2015/10 - 2020/07 Institut Cochin, University Paris 5/INSERM/CNRS (Paris, France); post-doctoral researcher
  • 2006/04 - 2015/09 The University of Tokyo
  • 2004/06 - 2006/03 三井記念病院内科レジデント
  • 2003/05 - 2004/05 東京大学医学部附属病院内科研修医
Awards (1):
  • 2017/04 - European Commission Seal of Excellence in Marie Skłodowska-Curie actions call H2020-MSCA-IF-2016 Functional Analysis and Deorphanization for Orphan Receptors of the Melatonin Receptor Subfamily
Association Membership(s) (3):
日本内科学会 ,  日本糖尿病学会 ,  日本解剖学会
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