Rchr
J-GLOBAL ID:202001018700160800   Update date: Jul. 15, 2024

Machida Kodai

マチダ コウダイ | Machida Kodai
Affiliation and department:
Job title: 准教授
Research field  (1): Systems genomics
Research keywords  (3): human cell-like liposome ,  chaprone ,  cell free protein synthesis
Research theme for competitive and other funds  (6):
  • 2023 - 2025 ポリアミンがCAGリピート由来の非標準翻訳に与える影響と翻訳開始点の解明
  • 2021 - 2025 変異型アクチンの試験管内バイオジェネシスとその分子機構の解析
  • 2021 - 2023 非典型翻訳の試験管内再構成とそのメカニズムの解明
  • 2017 - 2021 In vitro translation and analysis of neurodegenerative diseases
  • 2016 - 2019 Development of palm-sized ion gun and test of cell adhesion-activation for medical applications
Show all
Papers (29):
  • Kodai Machida, Rin Tanaka, Seraya Miki, Shotaro Noseda, Mayumi Yuasa-Sunagawa, Hiroaki Imataka. High-throughput screening for a SARS-CoV-2 frameshifting inhibitor using a cell-free protein synthesis system. BioTechniques. 2024. 76. 4. 161-168
  • Hayato Ito, Kodai Machida, Mayuka Hasumi, Morio Ueyama, Yoshitaka Nagai, Hiroaki Imataka, Hideki Taguchi. Reconstitution of C9orf72 GGGGCC repeat-associated non-AUG translation with purified human translation factors. Scientific reports. 2023. 13. 1. 22826-22826
  • Yosuke Ito, Yuhei Chadani, Tatsuya Niwa, Ayako Yamakawa, Kodai Machida, Hiroaki Imataka, Hideki Taguchi. Nascent peptide-induced translation discontinuation in eukaryotes impacts biased amino acid usage in proteomes. Nature communications. 2022. 13. 1. 7451-7451
  • Kodai Machida, Shoma Miyawaki, Kuru Kanzawa, Taiki Hakushi, Tomonori Nakai, Hiroaki Imataka. An in Vitro Reconstitution System Defines the Defective Step in the Biogenesis of Mutated β-Actin Proteins. ACS synthetic biology. 2021. 10. 11. 3158-3166
  • Chihiro Hirayama, Kodai Machida, Kentaro Noi, Tadayoshi Murakawa, Masaki Okumura, Teru Ogura, Hiroaki Imataka, Kenji Inaba. Distinct roles and actions of protein disulfide isomerase family enzymes in catalysis of nascent-chain disulfide bond formation. iScience. 2021. 24. 4. 102296-102296
more...
MISC (1):
  • 茶谷悠平, 伊藤遥介, 丹羽達也, 丹羽達也, 山川絢子, 町田幸大, 今高寛晃, 田口英樹, 田口英樹. 蛋白質の合成過程に潜む途上終結リスクは生物のプロテオームに配列的制約をもたらす. 日本蛋白質科学会年会プログラム・要旨集. 2023. 23rd (CD-ROM)
Education (4):
  • 2006 - 2009 Tottori University Graduate School of Medical Sciences Major in Regenerative Medicine and Biofunction
  • 2003 - 2005 Tottori University Graduate School of Medical Sciences Major in Regenerative Medicine and Biofunction
  • 1999 - 2003 Tottori University Faculty of Engineering Department of Biotechnology
  • 1996 - 1999 長崎県立諫早高等学校
Professional career (1):
  • Doctor of Philosophy in Regenerative Medicine (Tottori University)
Work history (3):
  • 2020/04 - 現在 University of Hyogo Graduate School of Engineering
  • 2009/04 - 2020/03 University of Hyogo Graduate School of Engineering
  • 2005/04 - 2006/03 Tottori University Faculty of Engineering
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