KAUSHIK Mahesh Kumar

カウシックマヘシュクマール | KAUSHIK Mahesh Kumar

Affiliation and department：
Job title： Assistant Professor

Research field (4)： Pharmacology , Neuroscience - general , Neuroscience - general , Neuroscience - general

Research keywords (5)： Seizure/Epilepsy , Pre-clinical studies , Narcolepsy/Cataplexy , Neurobiology of sleep-wakefulness , CNS Disorders

Research theme for competitive and other funds (7)：

2014 - 2020 Investigating the effects of orexin antagonists on sleep disorder narcolepsy and underlying molecular and cellular changes in brain architecture
2018 - 2019 Evaluation of the wake-inducing activity of novel compounds by Sumitomo Dainippon Pharma in murine models
2014 - 2018 Development of therapy for the treatment of cataplexy/narcolepsy by intrathecal orexin administration
2017 - 2018 Evaluation of novel compounds by MTPC for their wake-inducing potential and narcolepsy inhibiting activity in murine models.
2011 - 2018 Role of Prostaglandin D2 in epileptic seizures and post-ictal pathological sleep regulation

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Papers (9)：

Elhosainy, Asmaa, Suzuki-Abe, Haruka, Kaushik, Mahesh K, Kim, Staci J, Saitoh, Tsuyoshi, Ishikawa, Yukiko, Hotta-Hirashima, Noriko, Miyoshi, Chika, Funato, Hiromasa, et al. Face validation and pharmacologic analysis of Sik3^Sleepy mutant mouse as a possible model of idiopathic hypersomnia. EUROPEAN JOURNAL OF PHARMACOLOGY. 2023. 954
Elhosainy, Asmaa, Suzuki-Abe, Haruka, Kaushik, Mahesh K, Kim, Staci J, Saitoh, Tsuyoshi, Ishikawa, Yukiko, Hotta-Hirashima, Noriko, Miyoshi, Chika, Funato, Hiromasa, et al. Face validation and pharmacologic analysis of Sik3^Sleepy mutant mouse as a possible model of idiopathic hypersomnia. EUROPEAN JOURNAL OF PHARMACOLOGY. 2023. 954
Yang Lin, Koustav Roy, Shuji Ioka, Rintaro Otani, Mao Amezawa, Yukiko Ishikawa, Yoan Cherasse, Mahesh K Kaushik, Daniela Klewe-Nebenius, Li Zhou, et al. Positive allosteric adenosine A2A receptor modulation suppresses insomnia associated with mania- and schizophrenia-like behaviors in mice. Frontiers in pharmacology. 2023. 14. 1138666-1138666
Mahesh K. Kaushik, Kosuke Aritake, Yoan Cherasse, Rahul Sharma, Yoshihiro Urade. A gain-of-function study of amelioration of pentylenetetrazole-induced seizures by endogenous prostaglandin D2. Neuroscience Letters. 2018. 686. 140-144
Kaushik, Mahesh K, Aritake, Kosuke, Cherasse, Yoan, Sharma, Rahul, Urade, Yoshihiro. A gain-of-function study of amelioration of pentylenetetrazole-induced seizures by endogenous prostaglandin D. Neuroscience letters. 2018. 686. 140-144

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Lectures and oral presentations (34)：

Narcolepsy- sleep stress and orexin: Towards the development of new therapies
(XLI Annual Meeting of the Indian Academy of Neurosciences and International Conference on BRAIN: CHEMISTRY TO COGNITION)
Narcolepsy- sleep stress and orexin: Towards the development of new therapies
(India Sleep 2023 Conference of Indian Society for Sleep Research (ISSR))
Solving the mysteries of sleep: Narcolepsy- sleep stress and orexin
(Department of Pharmaceutical Sciences, Babasaheb Bhimrao Ambedkar University)
Solving the mysteries of sleep: Narcolepsy- sleep stress and orexin.
(Regional Center for Biotechnology (RCB),)
Solving the mysteries of sleep: Narcolepsy- sleep stress and orexin.
(Department of Physiology, All India Institute of Medical Sciences (AIIMS),)

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Education (3)：

2005 - 2010 All India Institute of Medical Sciences (AIIMS), New Delhi, India. Department of Physiology. Ph.D.
2002 - 2004 Jiwaji University, Gwalior, Madhya pradesh, India School of Studies in Neuroscience. M.Sc.
1998 - 2001 Maharashi Dayananda University, Rohtak, Haryana Pt. Jawahar Lal Nahru College, Faridabad. B.Sc.

Work history (7)：

2024/07 - 現在 University of Tsukuba International Institute for Integrative Sleep Medicine Assistant Professor
2022/04 - 2024/07 University of Tsukuba University of Tsukuba Assistant Professor
2021/08 - 現在 University of Tsukuba, Tsukuba, Ibaraki, Japan International Institute for Integrative Sleep Medicine (IIIS). Assistant Professor
2014/09 - 2021/07 International Institute for Integrative Sleep Medicine (WPI-IIIS), University of Tsukuba, Ibaraki, Japan Molecular Genetics of Sleep (Yanagisawa Lab). Researcher
2014/04 - 2014/08 Indiana University of School of Medicine, South Bend, IN, USA Department of Toxicology and Pharmacology. Postdoctoral Fellow

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Awards (9)：

2011/03 - Takeda Science Foundation Takeda Science Foundation Award for Research In Japan Postdoctoral fellowship, Osaka Bioscience Institute (OBI), Osaka, Japan
2011/03 - Takeda Science Foundation Postdoctoral Fellowship for Research In Japan Osaka Bioscience Institute (OBI), Osaka, Japan
2010/12 - Indian Society for Sleep Research (ISSR) 4th conference of Indian Society for Sleep Research (ISSR), Trivandrum, India Best Paper Award, ISSR Conference
2010/12 - Indian Society for Sleep Research (ISSR) Best Paper Award 4th conference of Indian Society for Sleep Research (ISSR), Trivandrum, India
2009/12 - Asia Pacific Society for Neuroscience Travel Award ISN/APSN/IBRO/SNCI advance school on neurodegenerative diseases, Cochin, India

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Association Membership(s) (4)：

Japanese Society for Sleep Research (JSSR) , Indian Society for Sleep Research (ISSR) , Association of Physiologists and Pharmacologist of India , Indian Academy of Neuroscience

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