2019 - 2022 Analysis of airway mucociliary transport via Toll-like receptors pathway
2019 - 2022 Development of novel immune combination therapy for interstitial pneumonia associated with connective tissue disease
2018 - 2021 Development of a novel vaccine against intracellular bacterial infection by inhibiting immune checkpoint molecules
2017 - 2021 Changes in pulmonary endothelial cell and fibroblast properties during bleomycin-induced pulmonary fibrosis
2017 - 2020 Development of a novel T cell-oriented vaccine using CTL/Th-bi-epitope long peptide and biodegradable microparticles, against an intracellular bacterium
2016 - 2019 Differentiation of follicular helper T cells induced by lung dendritic cells in asthma
2015 - 2018 Development of novel dendritic -cell vaccine with biodegradable nanoparticles for tuberculosis
2015 - 2018 Immunotherapy for lung cancer with pulmonary fibrosis
2014 - 2017 The cross-talk between innate immunity and acquired immunity in exacerbation of airway inflammation in asthmatic attack
2013 - 2016 Development of a novel vaccine therapy using nanoparticles and cross-presentation machinery
2012 - 2015 Type 1-polarized dendritic cells pulsed with ESAT-6 are a potent immunogen against tuberculosis
2012 - 2015 Class-switching of immunoglobulins induced by pneumococcal vaccine
2009 - 2011 Novel dendritic cell vaccine for tuberculosis with inhibition of indoleamine 2, 3-dioxygenase.
2009 - 2011 Type-1 polarized dendritic cell vaccine for tuberculosis
2008 - 2010 A novel tuberculosis vaccine strategy to regulate the latent infection and resuscitation of Mycobacterium tuberculosis
2007 - 2008 Development of dendritic cell vaccine modified with a ligand of NKT cells against tuberculosis
2007 - 2008 Superantigen pulsed DCs supports the induction of tumor immunity
2005 - 2007 Development of heterologous vaccines using MPT51, a novel secretory protein of Mycobacterium tubeiculosis
2005 - 2006 Crosstalk and the regulation of intestinal immune cells: mucosal dendritic cells and intraepithelial lymphocytes
2005 - 2006 Intratracheal injection of dendritic cells loaded with cytotoxic T cell epitope of intracellular pathogen efficiently induces epitope-specific T cells and confers protective immunity
2003 - 2004 優位阻害型レチノイン酸受容体の肺特異的、時相特異的発現マウスの開発
2003 - 2004 Development of anti-tuberculosis vaccine using cytokine gene-transduced dendritic cells
2003 - 2004 Immunohistochemical study of cell cycle regulators in idiopathic pulmonary fibrosis
2001 - 2002 Development of DC-vaccine against tuberclulosis
2001 - 2002 The significance of expression of CD1 family by dendritic cells in human sarcoid lesions
2000 - 2001 THE STUDY OF THE EXPRESSIONS AND FUNCTIONS OF NUCLEAR HORMONE RECEPTORS IN HUMAN ALVEOLAR MACROPHAGES
1999 - 2000 Involvement of dendritic cells in pulmonary granuloma formation elicited by BCG in rats
1997 - 1998 肺内樹状細胞の分布,表面抗原および抗原提示能に加齢が及ぼす影響
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Papers (1,167)：
Yuko Tanaka, Tomoyuki Fujisawa, Shusuke Yazawa, Isao Ohta, Yasuharu Takaku, Masahiko Ito, Yusuke Inoue, Hideki Yasui, Hironao Hozumi, Masato Karayama, et al. Obesity impairs ciliary function and mucociliary clearance in the murine airway epithelium. American journal of physiology. Lung cellular and molecular physiology. 2024
Hironao Hozumi, Koichi Miyashita, Eiji Nakatani, Yusuke Inoue, Hideki Yasui, Yuzo Suzuki, Masato Karayama, Kazuki Furuhashi, Noriyuki Enomoto, Tomoyuki Fujisawa, et al. Antifibrotics and mortality in idiopathic pulmonary fibrosis: external validity and avoidance of immortal time bias. Respiratory research. 2024. 25. 1. 293-293
Hiromitsu Sumikawa, Takeshi Johkoh, Ryoko Egashira, Hiroaki Sugiura, Chikatoshi Sugimoto, Tomonori Tanaka, Masahisa Nakamura, Akihiro Kuriu, Noriyuki Tomiyama, Tomoyuki Fujisawa, et al. Variability of radiological and clinical features in cases with usual interstitial pneumonia without honeycombing. European journal of radiology. 2024. 179. 111651-111651
Masahiro Umemura, Akira Honda, Maho Yamashita, Takeshi Chida, Hidenao Noritake, Kenta Yamamoto, Takashi Honda, Mayuko Ichimura-Shimizu, Koichi Tsuneyama, Teruo Miyazaki, et al. High-fat diet modulates bile acid composition and gut microbiota, affecting severe cholangitis and cirrhotic change in murine primary biliary cholangitis. Journal of autoimmunity. 2024. 148. 103287-103287
Hiromitsu Sumikawa, Kosaku Komiya, Ryoko Egashira, Junya Tominaga, Midori Ueno, Taiki Fukuda, Daisuke Yamada, Reoto Takei, Kensuke Kataoka, Tomoki Kimura, et al. Validation of a computed tomography diagnostic model for differentiating fibrotic hypersensitivity pneumonitis from idiopathic pulmonary fibrosis. Respiratory investigation. 2024. 62. 5. 798-803
宮下晃一, 穗積宏尚, 古橋一樹, 中谷英仁, 尾島俊之, 須田隆文. Experience of research using the NDB onsite research center-Nation-wide survey of COVID-19 patients in Japan-. 医療情報学連合大会論文集(CD-ROM). 2023. 43rd
宮下晃一, 穗積宏尚, 古橋一樹, 中谷英仁, 井上裕介, 安井秀樹, 鈴木勇三, 柄山正人, 榎本紀之, 藤澤朋幸, et al. COVID-19 mortality in patients with interstitial lung disease: a large-scale nationwide database study. 日本呼吸器学会誌(Web). 2023. 12
