Research theme for competitive and other funds (3)：
2023 - 2026 がん特異的プロドラッグ化を目指した毒性ペプチドの立体的マスク化
2021 - 2024 The use of nucleic acid aptamers as a removable masking agent for the controlled polymer modification of enzymes
2020 - 2022 Design and development of artificial scaffolds capturing vascular endothelial progenitor cells with high efficiency for accelerating endothelialization
Papers (4)：
Yasushi Sasai, Daiki Ousaka, Yasuhiro Fujii, Aoi Isono, Yukinori Yamauchi, Shin-ichi Kondo, Tatsuyuki Nakatiani. Surface Functionalization of Diamond-like Carbon Film with Biocompatible Polymer Brushes. Journal of Photopolymer Science and Technology. 2022. 35. 4. 303-308
Aoi Isono, Mieko Tsuji, Yu Sanada, Akari Matsushita, Shinichiro Masunaga, Tasuku Hirayama, Hideko Nagasawa. Design, Synthesis, and Evaluation of Lipopeptide Conjugates of Mercaptoundecahydrododecaborate for Boron Neutron Capture Therapy. ChemMedChem. 2019. 14. 8. 823-832
Takahiko Imai, Keisuke Mishiro, Toshinori Takagi, Aoi Isono, Hideko Nagasawa, Kazuhiro Tsuruma, Masamitsu Shimazawa, Hideaki Hara. Protective Effect of Bendavia (SS-31) Against Oxygen/Glucose-Deprivation Stress-Induced Mitochondrial Damage in Human Brain Microvascular Endothelial Cells. Current neurovascular research. 2017. 14. 1. 53-59
Mieko Tsuji, Satoshi Ueda, Tasuku Hirayama, Kensuke Okuda, Yoshiaki Sakaguchi, Aoi Isono, Hideko Nagasawa. FRET-based imaging of transbilayer movement of pepducin in living cells by novel intracellular bioreductively activatable fluorescent probes. Organic & biomolecular chemistry. 2013. 11. 18. 3030-7
MISC (2)：
Isono A, Okuda K, Hirayama T, Masunaga S, Nagasawa H. Development of Nuder-targeting Boron Carriers Based on the Chemistry of Direct Cell-penetrating Pepducins. Progress Report 2014, The Research Reactor Institute, Kyoto University. 2015. 5
Isono A, Okuda K, Hirayama T, Masunaga S, Nagasawa H. Design and Synthesis of a New Membrane Peameable Boron Carrier Using the Lipidated Peptide Vehicle. Progress Report 2013, The Research Reactor Institute, Kyoto University. 2014. 121
