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J-GLOBAL ID：202002210173708302   Reference number：20A0708041

Interleukin-17A/F1 Deficiency Reduces Antimicrobial Gene Expression and Contributes to Microbiome Alterations in Intestines of Japanese medaka (Oryzias latipes)

インターロイキン17A/F1欠損は,日本メダカ(Oryzias latipes)の腸における抗菌遺伝子発現を減少させ,ミクロビオーム変化に寄与する【JST・京大機械翻訳】

Author (13)： Okamura Yo (Interdisciplinary Graduate School of Agriculture and Engineering, University of Miyazaki, Miyazaki, Japan) ,  Morimoto Natsuki (Interdisciplinary Graduate School of Agriculture and Engineering, University of Miyazaki, Miyazaki, Japan) ,  Ikeda Daisuke (School of Marine Biosciences, Kitasato University, Sagamihara, Japan) ,  Mizusawa Nanami (School of Marine Biosciences, Kitasato University, Sagamihara, Japan) ,  Watabe Shugo (School of Marine Biosciences, Kitasato University, Sagamihara, Japan) ,  Miyanishi Hiroshi (Department of Marine Biology and Environmental Science, Faculty of Agriculture, University of Miyazaki, Miyazaki, Japan) ,  Saeki Yuichi (Department of Biochemistry and Applied Bioscience, Faculty of Agriculture, University of Miyazaki, Miyazaki, Japan) ,  Takeyama Haruko (Department of Life Science and Medical Bioscience, School of Advanced Science and Engineering, Waseda University, Tokyo, Japan) ,  Aoki Takashi (Integrated Institute for Regulatory Science, Research Organization for Nao and Life Innovation, Waseda University, Tokyo, Japan) ,  Kinoshita Masato (Division of Applied Bioscience, Graduate School of Agriculture, Kyoto University, Kyoto, Japan) ,  Kono Tomoya (Department of Biochemistry and Applied Bioscience, Faculty of Agriculture, University of Miyazaki, Miyazaki, Japan) ,  Sakai Masahiro (Department of Biochemistry and Applied Bioscience, Faculty of Agriculture, University of Miyazaki, Miyazaki, Japan) ,  Hikima Jun-ichi (Department of Biochemistry and Applied Bioscience, Faculty of Agriculture, University of Miyazaki, Miyazaki, Japan)
Material： Frontiers in Immunology (Web)
Volume： 11  Page： 425  Publication year： 2020 
JST Material Number： U7074A  ISSN： 1664-3224  Document type： Article
Article type： 原著論文  Country of issue： Switzerland (CHE)  Language： ENGLISH (EN)

Abstract/Point： In mammals, interleukin (IL)-1...

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Thesaurus term： lysozyme ,  *interleukin ,  wild type ,  down-regulation ,  Enterobacteriaceae ,  *interleukin 1 ,  Mammalia ,  intestinal mucosa ,  homeostasis ,  human(primates) ,  *gene ,  *gene expression ,  *killifish ,  pathogen ,  quantitative polymerase chain reaction

Author keywords (7)： genome editing ,  interleukin-17A/F1 ,  Japanese medaka ,  Oryzias latipes ,  transcriptome analysis ,  metagenomics ,  teleosts

JST classification (3)： Intestines  (EJ06040N) ,  Basic medicine on digestive system  (GH01020E) ,  Cytokines  (EB08090G)

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Terms in the title (9)： インターロイキン17A ,  欠損 ,  日本 ,  メダカ ,  Oryzias ,  腸 ,  抗菌 ,  遺伝子発現 ,  ミクロビオーム