Art

J-GLOBAL ID：202002210557805891   Reference number：20A2731797

Oxidative Stress in Amyotrophic Lateral Sclerosis: Pathophysiology and Opportunities for Pharmacological Intervention

筋萎縮性側索硬化症における酸化ストレス:薬理学的介入のための病態生理学と機会【JST・京大機械翻訳】

Author (9)： Cunha-Oliveira Teresa (CNC-Center for Neuroscience and Cell Biology, University of Coimbra, UC Biotech Building, Biocant Park, Cantanhede, Portugal) ,  Montezinho Liliana (CNC-Center for Neuroscience and Cell Biology, University of Coimbra, UC Biotech Building, Biocant Park, Cantanhede, Portugal) ,  Montezinho Liliana (Center for Investigation Vasco da Gama (CIVG), Escola Universitaria Vasco da Gama, Coimbra, Portugal) ,  Mendes Catarina (CNC-Center for Neuroscience and Cell Biology, University of Coimbra, UC Biotech Building, Biocant Park, Cantanhede, Portugal) ,  Mendes Catarina (Coimbra College of Agriculture, Polytechnic Institute of Coimbra (ESAC, IPC), Bencanta, Coimbra, Portugal) ,  Firuzi Omidreza (Medicinal and Natural Products Chemistry Research Center, Shiraz University of Medical Sciences, Shiraz, Iran) ,  Saso Luciano (Department of Physiology and Pharmacology “Vittorio Erspamer”, Sapienza University of Rome, Italy) ,  Oliveira Paulo J. (CNC-Center for Neuroscience and Cell Biology, University of Coimbra, UC Biotech Building, Biocant Park, Cantanhede, Portugal) ,  Silva Filomena S. G. (CNC-Center for Neuroscience and Cell Biology, University of Coimbra, UC Biotech Building, Biocant Park, Cantanhede, Portugal)
Material： Oxidative Medicine and Cellular Longevity (Web)  (Oxidative Med Cell Longev (Web))
Volume： 2020  Page： Null  Publication year： 2020 
JST Material Number： U7012A  ISSN： 1942-0900  Document type： Article
Article type： 文献レビュー  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Abstract/Point： Amyotrophic lateral sclerosis ...

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Thesaurus term： document retrieval ,  motor nerve ,  clinical trial ,  antioxidation ,  *pharmacology ,  characterization ,  *amyotrophic lateral sclerosis ,  *oxidative stress
Semi thesaurus term： 神経変性疾患 ,  神経変性 ,  動物モデル ,  抗酸化剤 ,  ミトコンドリア機能障害 ,  抗酸化防御 ,  ミトコンドリア機能 , 【Automatic Indexing@JST】

JST classification (2)： Nervous system diseases  (GN03000O) ,  Basic neurology  (GN01020W)

Reference (279)：

• F. Tafuri, D. Ronchi, F. Magri, G. P. Comi, S. Corti, "SOD1 misplacing and mitochondrial dysfunction in amyotrophic lateral sclerosis pathogenesis," Frontiers in Cellular Neuroscience, vol. 9, pp. 336, 2015.
• S. Zarei, K. Carr, L. Reiley, K. Diaz, O. Guerra, P. F. Altamirano, W. Pagani, D. Lodin, G. Orozco, A. Chinea, "A comprehensive review of amyotrophic lateral sclerosis," Surgical Neurology International, vol. 6, no. 1, pp. 171, 2015.
• E. F. Smith, P. J. Shaw, K. J. De Vos, "The role of mitochondria in amyotrophic lateral sclerosis," Neuroscience Letters, vol. 710, article 132933, 2019.
• M. Tanaka, T. Sakata, J. Palumbo, M. Akimoto, "A 24-week, phase III, double-blind, parallel-group study of edaravone (MCI-186) for treatment of amyotrophic lateral sclerosis (ALS) (P3.189)," Neurology, vol. 86, 2016.
• The Writing Group, Edaravone (MCI-186) ALS 19 Study Group et al., "Safety and efficacy of edaravone in well defined patients with amyotrophic lateral sclerosis: a randomised, double-blind, placebo-controlled trial," The Lancet Neurology, vol. 16, no. 7, pp. 505-512, 2017.

Terms in the title (5)： 筋萎縮性側索硬化症 ,  酸化ストレス ,  薬理学 ,  病態生理学 ,  機会