Art

J-GLOBAL ID：202002210772224978   Reference number：20A2696524

Microglia Diversity in Health and Multiple Sclerosis

健康と多発性硬化症におけるミクログリア多様性【JST・京大機械翻訳】

Author (9)： Zia Sameera (1Neuroscience and Mental Health Institute, University of Alberta, Edmonton, AB, Canada) ,  Rawji Khalil S. (2Wellcome Trust-Medical Research Council Cambridge Stem Cell Institute, Jeffrey Cheah Biomedical Campus, Cambridge Biomedical Campus, University of Cambridge, Cambridge, United Kingdom) ,  Michaels Nathan J. (3Ministry of Health, British Columbia Government, Victoria, BC, Canada) ,  Burr Mena (1Neuroscience and Mental Health Institute, University of Alberta, Edmonton, AB, Canada) ,  Kerr Bradley J. (1Neuroscience and Mental Health Institute, University of Alberta, Edmonton, AB, Canada) ,  Kerr Bradley J. (4Department of Anesthesiology & Pain Medicine, University of Alberta, Edmonton, AB, Canada) ,  Healy Luke M. (5Neuroimmunology Unit, Department of Neurology and Neurosurgery, Montreal Neurological Institute and Hospital, McGill University, Montreal, QC, Canada) ,  Plemel Jason R. (1Neuroscience and Mental Health Institute, University of Alberta, Edmonton, AB, Canada) ,  Plemel Jason R. (6Department of Medicine, Division of Neurology, University of Alberta, Edmonton, AB, Canada)
Material： Frontiers in Immunology (Web)
Volume： 11  Page： 588021  Publication year： 2020 
JST Material Number： U7074A  ISSN： 1664-3224  Document type： Article
Article type： 文献レビュー  Country of issue： Switzerland (CHE)  Language： ENGLISH (EN)

Abstract/Point： Multiple Sclerosis (MS) is a n...

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Thesaurus term： mass spectrometry ,  RNA ,  inflammation ,  phenotype ,  senile change ,  autoimmunity ,  macrophage ,  monocyte ,  *multiple sclerosis ,  *microglia
Semi thesaurus term： 免疫系 ,  神経変性疾患 ,  免疫細胞 ,  単一細胞 ,  神経保護 , 【Automatic Indexing@JST】

Author keywords (7)： microglia ,  macrophages ,  single-cell analysis ,  single-cell RNA sequencing ,  multiple sclerosis ,  remyelination ,  ageing

JST classification (1)： Basic neurology  (GN01020W)

Reference (166)：

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• MittelbronnMDietzKSchluesenerHJMeyermannR. Local distribution of microglia in the normal adult human central nervous system differs by up to one order of magnitude. Acta Neuropathol (2001) 101(3):249-55. doi: doi: 10.1007/s004010000284
• LiQBarresBA. Microglia and macrophages in brain homeostasis and disease. Nat Rev Immunol (2018) 18(4):225-42. doi: doi: 10.1038/nri.2017.125
• GinhouxFLimSHoeffelGLowDHuberT. Origin and differentiation of microglia. Front Cell Neurosci (2013) 7:45. doi: doi: 10.3389/fncel.2013.00045
• PaolicelliRCGrossCT. Microglia in development: linking brain wiring to brain environment. Neuron Glia Biol (2011) 7(1):77-83. doi: doi: 10.1017/S1740925X12000105

Terms in the title (3)： 多発性硬化症 ,  ミクログリア ,  多様性