Art

J-GLOBAL ID：202002211163839822   Reference number：20A2511907

Distinct Roles of IL-1β and IL-18 in NLRC4-Induced Autoinflammation

NLRC4誘発自己炎症におけるIL-1βとIL-18の異なる役割【JST・京大機械翻訳】

Author (8)： Sasaki Yuki (1Department of Immunology and Parasitology, Graduate School of Medicine, Tokushima University, Tokushima, Japan) ,  Otsuka Kunihiro (2Department of Interdisciplinary Researches for Medicine and Photonics, Institute of Post-LED Photonics, Tokushima University, Tokushima, Japan) ,  Arimochi Hideki (1Department of Immunology and Parasitology, Graduate School of Medicine, Tokushima University, Tokushima, Japan) ,  Tsukumo Shin-Ichi (1Department of Immunology and Parasitology, Graduate School of Medicine, Tokushima University, Tokushima, Japan) ,  Tsukumo Shin-Ichi (2Department of Interdisciplinary Researches for Medicine and Photonics, Institute of Post-LED Photonics, Tokushima University, Tokushima, Japan) ,  Yasutomo Koji (1Department of Immunology and Parasitology, Graduate School of Medicine, Tokushima University, Tokushima, Japan) ,  Yasutomo Koji (2Department of Interdisciplinary Researches for Medicine and Photonics, Institute of Post-LED Photonics, Tokushima University, Tokushima, Japan) ,  Yasutomo Koji (3The Research Cluster Program on Immunological Diseases, Tokushima University, Tokushima, Japan)
Material： Frontiers in Immunology (Web)
Volume： 11  Page： 591713  Publication year： 2020 
JST Material Number： U7074A  ISSN： 1664-3224  Document type： Article
Article type： 原著論文  Country of issue： Switzerland (CHE)  Language： ENGLISH (EN)

Abstract/Point： The NLRC4 inflammasome assembl...

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Thesaurus term： bacterium ,  *inflammation ,  mutation ,  spleen ,  promoter(genetics) ,  neutrophils ,  transgenic mouse ,  cytokine ,  *interleukin 1 ,  cell death ,  MHC class II antigen ,  bone density
Semi thesaurus term： *インターロイキン18 ,  *インターロイキン1β ,  インフラマソーム , 【Automatic Indexing@JST】

Author keywords (5)： autoinflammation ,  NLRC4 ,  interleukin-1β ,  interleukin-18 ,  bone

JST classification (2)： Biological function  (EB03040U) ,  Biophylaxis and immune systems in general  (ED01010F)

Reference (30)：

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• AksentijevichIKastnerDL. Genetics of monogenic autoinflammatory diseases: past successes, future challenges. Nat Rev Rheumatol (2011) 7:469-78. doi: doi: 10.1038/nrrheum.2011.94

Terms in the title (7)： NLRC4 ,  誘発 ,  自己 ,  炎症 ,  IL-1β ,  IL-18 ,  役割