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J-GLOBAL ID：202002211200813831   Reference number：20A2769185

Identification of a Transcriptomic Prognostic Signature by Machine Learning Using a Combination of Small Cohorts of Prostate Cancer

前立腺癌の小コホートの組合せを用いた機械学習によるトランスクリプトーム予後シグネチャの同定【JST・京大機械翻訳】

Author (14)： Vittrant Benjamin (Centre de Recherche du CHU de Quebec - Universite Laval, Quebec, QC, Canada) ,  Vittrant Benjamin (Departement de Medecine Moleculaire, Universite Laval, QC, Canada) ,  Leclercq Mickael (Centre de Recherche du CHU de Quebec - Universite Laval, Quebec, QC, Canada) ,  Leclercq Mickael (Departement de Medecine Moleculaire, Universite Laval, QC, Canada) ,  Martin-Magniette Marie-Laure (Universities of Paris Saclay, Paris, Evry, CNRS, INRAE, Institute of Plant Sciences Paris Saclay (IPS2), 91192, GIf sur Yvette, France) ,  Martin-Magniette Marie-Laure (UMR MIA-Paris, AgroParisTech, INRA, Universite Paris-Saclay, Paris, France) ,  Collins Colin (Vancouver Prostate Cancer Centre, Vancouver, BC, Canada) ,  Collins Colin (Department of Urologic Sciences, The University of British Columbia, Vancouver, BC, Canada) ,  Bergeron Alain (Centre de Recherche du CHU de Quebec - Universite Laval, Quebec, QC, Canada) ,  Bergeron Alain (Departement de Chirurgie, Oncology Axis, Universite Laval, Quebec, QC, Canada) ,  Fradet Yves (Centre de Recherche du CHU de Quebec - Universite Laval, Quebec, QC, Canada) ,  Fradet Yves (Departement de Chirurgie, Oncology Axis, Universite Laval, Quebec, QC, Canada) ,  Droit Arnaud (Centre de Recherche du CHU de Quebec - Universite Laval, Quebec, QC, Canada) ,  Droit Arnaud (Departement de Medecine Moleculaire, Universite Laval, QC, Canada)
Material： Frontiers in Genetics (Web)
Volume： 11  Page： 550894  Publication year： 2020 
JST Material Number： U7071A  ISSN： 1664-8021  Document type： Article
Article type： 原著論文  Country of issue： Switzerland (CHE)  Language： ENGLISH (EN)

Abstract/Point： Determining which treatment to...

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Thesaurus term： RNA ,  gene ,  *prognosis ,  *population(statistics) ,  robustness ,  *prostatic tumor ,  misdiagnosis ,  biomarker ,  *machine learning ,  prostate-specific antigen ,  *transcriptome
Semi thesaurus term： 臨床病理学 ,  トランスクリプトーム解析 ,  臨床医 ,  ランダムフォレスト , 【Automatic Indexing@JST】

Author keywords (6)： machine learning ,  prostate cancer ,  RNA-seq ,  biochemical recurrence ,  random forest ,  predictive signature

JST classification (1)： Urogenital tumors(=neoplasms)  (GM04000S)

Reference (98)：

• Abou-OufH.AlshalalfaM.TakharM.ErhoN.DonnellyB.DavicioniE. (2018). Validation of a 10-gene molecular signature for predicting biochemical recurrence and clinical metastasis in localized prostate cancer. J. Cancer Res. Clin. Oncol. 144 883-891. doi: 10.1007/s00432-018-2615-7 29511883
• Al-JarrahO. Y.YooP. D.MuhaidatS.KaragiannidisG. K.TahaK. (2015). Efficient machine learning for big data: a review. Big Data Res. 2 87-93. doi: 10.1016/j.bdr.2015.04.001
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• AndrewsS.KruegerF.Segonds-PichonA.BigginsL.KruegerC.WingettS. (2010). FastQC: A Quality Control Tool for High Throughput Sequence Data. Babraham: Babraham Institute.

Terms in the title (8)： 前立腺癌 ,  コホート ,  組合せ ,  機械学習 ,  トランスクリプトーム ,  予後 ,  シグネチャ ,  同定