Art

J-GLOBAL ID：202002212019335192   Reference number：20A1608138

Extracellular signal-regulated kinases (ERK) 1 and 2 as a key molecule in pain research

疼痛研究における重要な分子としての細胞外シグナル調節キナーゼ(ERK)1および2

Author (2)： Kondo Masahiro (Department of Legal Medicine, Nihon University School of Dentistry) ,  Shibuta Ikuko (Department of Physiology, Nihon University School of Dentistry)
Material： Journal of Oral Science  (J Oral Sci)
Volume： 62  Issue： 2  Page： 147-149(J-STAGE)  Publication year： 2020 
JST Material Number： Z0759A  ISSN： 1343-4934  Document type： Article
Article type： 解説  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *pain ,...
Semi thesaurus term： *cellular signal transduction ,...

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Author keywords (6)： ERK phosphorylation ,  inflammation ,  nociception ,  pain ,  peripheral nerve injury ,  tissue damage

JST classification (1)： Basic neurology  (GN01020W)

Reference (39)：

• 1. Woolf CJ (2004) Pain: moving from symptom control toward mechanism-specific pharmacologic management. Ann Intern Med 140, 441-451.
• 2. Ueda H (2008) Peripheral mechanisms of neuropathic pain-involvement of lysophosphatidic acid receptor-mediated demyelination. Mol Pain 4,11.
• 3. Julius D, Basbaum (2001) Molecular mechanism of nocieption. Nature 413, 203-210.
• 4. Cruz CD, Cruz F (2007) The ERK 1 and 2 pathway in the nervous system: from basic aspects to possible clinical applications in pain and visceral dysfunction. Curr Neuropharmacol 5, 244-252.
• 5. Ji RR, Gereau RW 4th, Malcangio M, Strichartz GR (2009) MAP kinase and pain. Brain Res Rev 60, 135-148.

Terms in the title (5)： 疼痛 ,  研究 ,  分子 ,  細胞外シグナル調節キナーゼ ,  ERK