Art

J-GLOBAL ID：202002212715164433   Reference number：20A0626334

The Steps to Therapeutic Drug Monitoring: A Structured Approach Illustrated With Imatinib

治療薬モニタリングへのステップ:イマチニブにより例示された構造化アプローチ【JST・京大機械翻訳】

Author (11)： Buclin Thierry (1Service of Clinical Pharmacology, Department of Laboratory Medicine and Pathology, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland) ,  Thoma Yann (2School of Management and Engineering Vaud (HEIG-VD), University of Applied Science Western Switzerland (HES-SO), Yverdon-les-Bains, Switzerland) ,  Widmer Nicolas (1Service of Clinical Pharmacology, Department of Laboratory Medicine and Pathology, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland) ,  Widmer Nicolas (3Pharmacy of Eastern Vaud Hospitals, Rennaz, Switzerland) ,  Widmer Nicolas (4Institute of Pharmaceutical Sciences of Western Switzerland, University of Geneva, Geneva, Switzerland) ,  Andre Pascal (1Service of Clinical Pharmacology, Department of Laboratory Medicine and Pathology, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland) ,  Guidi Monia (1Service of Clinical Pharmacology, Department of Laboratory Medicine and Pathology, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland) ,  Guidi Monia (4Institute of Pharmaceutical Sciences of Western Switzerland, University of Geneva, Geneva, Switzerland) ,  Csajka Chantal (4Institute of Pharmaceutical Sciences of Western Switzerland, University of Geneva, Geneva, Switzerland) ,  Csajka Chantal (5Center for Research and Innovation in Clinical Pharmaceutical Sciences, Institute of Pharmaceutical Sciences of Western Switzerland, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland) ,  Decosterd Laurent A. (1Service of Clinical Pharmacology, Department of Laboratory Medicine and Pathology, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland)
Material： Frontiers in Pharmacology (Web)
Volume： 11  Page： 177  Publication year： 2020 
JST Material Number： U7091A  ISSN： 1663-9812  Document type： Article
Article type： 文献レビュー  Country of issue： Switzerland (CHE)  Language： ENGLISH (EN)

Abstract/Point： Pharmacometric methods have hu...

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Thesaurus term： pharmacodynamics ,  effectiveness ,  genome ,  pharmacology ,  targeting ,  *antitumor drug ,  computer science ,  molecular target therapy
Semi thesaurus term： 治療モニタリング ,  治療標的 ,  薬物濃度 ,  薬物反応 ,  患者介護 ,  臨床開発 , 【Automatic Indexing@JST】

Author keywords (6)： drug monitoring ,  molecular targeted therapies ,  pharmacokinetic-pharmacodynamic models ,  pharmacometrics ,  precision medicine ,  dosage individualization

JST classification (5)： Drug therapy(=pharmacotherapy)for tumors  (GE03032C) ,  Drug therapy(=pharmacotherapy)for urogenital diseases  (GM05020V) ,  Cell physiology in general  (EF02010S) ,  Medical materials  (GA05040H) ,  Structure and chemistry of genes  (EC02020U)

Substance index (1)： Imatinib

Reference (81)：

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• Bouchet S., Poulette S., Titier K., Moore N., Lassalle R., Abouelfath A., et al. (2016). Relationship between imatinib trough concentration and outcomes in the treatment of advanced gastrointestinal stromal tumours in a real-life setting. Eur. J. Cancer 57, 31-38. doi: doi: 10.1016/j.ejca.2015.12.029
• Buclin T., Widmer N., Biollaz J., Decosterd L. A. (2011). Who is in charge of assessing therapeutic drug monitoring? the case of imatinib. Lancet Oncol. 12, 9-11. doi: doi: 10.1016/S1470-2045(10)70258-8
• Buclin T., Gotta V., Fuchs A., Widmer N., Aronson J. (2012). Monitoring drug therapy. Br. J. Clin. Pharmacol. 73, 917-923. doi: doi: 10.1111/j.1365-2125.2012.04237.x

Terms in the title (4)： 治療薬 ,  モニタリング ,  イマチニブ ,  構造化