Art

J-GLOBAL ID：202002212794135763   Reference number：20A1172849

Apical-basal polarity inhibits epithelial-mesenchymal transition and tumour metastasis by PAR-complex-mediated SNAI1 degradation

頂端-基底極性は,PAR-複合体媒介Sni1分解により上皮間葉転換と腫瘍転移を阻害する【JST・京大機械翻訳】

Author (8)： Jung Hae-Yun (Department of Pharmacology, Moores Cancer Center, University of California, San Diego, La Jolla, CA, USA) ,  Fattet Laurent (Department of Pharmacology, Moores Cancer Center, University of California, San Diego, La Jolla, CA, USA) ,  Tsai Jeff H. (Department of Pharmacology, Moores Cancer Center, University of California, San Diego, La Jolla, CA, USA) ,  Kajimoto Taketoshi (Department of Pharmacology, Moores Cancer Center, University of California, San Diego, La Jolla, CA, USA) ,  Chang Qiang (Department of Medical Genetics and Department of Neurology, Waisman Center, University of Wisconsin-Madison, Madison, WI, USA) ,  Newton Alexandra C. (Department of Pharmacology, Moores Cancer Center, University of California, San Diego, La Jolla, CA, USA) ,  Yang Jing (Department of Pharmacology, Moores Cancer Center, University of California, San Diego, La Jolla, CA, USA) ,  Yang Jing (Department of Pediatrics, School of Medicine, University of California San Diego, La Jolla, CA, USA)
Material： Nature Cell Biology  (Nat Cell Biol)
Volume： 21  Issue： 3  Page： 359-371  Publication year： 2019 
JST Material Number： W1369A  ISSN： 1465-7392  Document type： Article
Article type： 原著論文  Country of issue： Germany, Federal Republic of (DEU)  Language： ENGLISH (EN)

Abstract/Point： Abstract: Loss of apical-basal...

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Thesaurus term： plasticity ,  *epithelium ,  Proteins ,  human ,  phosphorylation ,  *complex (substance) ,  heterotrans plantation ,  *metastasis ,  three dimension ,  mesenchyme ,  tumor invasion ,  breast tumor ,  aPKC ,  *Epithelial-Mesenchymal Transition ,  kinase ,  mechanical property ,  property ,  *membrane and film ,  *histomembrane

JST classification (2)： Cell physiology in general  (EF02010S) ,  Chemistry,biochemistry and pathology of tumors(=neoplasms)  (GE02030N)

Terms in the title (8)： 基底 ,  極性 ,  PAR ,  複合体 ,  分解 ,  上皮間葉転換 ,  腫瘍転移 ,  阻害