Art

J-GLOBAL ID：202002213235092008   Reference number：20A0385012

CRBN knockdown mitigates lipopolysaccharide-induced acute lung injury by suppression of oxidative stress and endoplasmic reticulum (ER) stress associated NF-κB signaling

CRBNノックダウンは酸化ストレスと小胞体(ER)ストレス関連NF-κBシグナル伝達の抑制によりリポ多糖類誘発急性肺損傷を緩和する【JST・京大機械翻訳】

Author (3)： Yang Huobao (Department of Critical Care Medicine, Shengli Clinical Medical College of Fujian Medical University, Fujian Provincial Hospital , Fuzhou, Fujian 350001, China) ,  Song Zhen (Department of Critical Care Medicine, Shandong Yuncheng County Chinese Medicine Hospital, Yuncheng County, Shandong Province, 274700, China) ,  Hong Donghuang (Department of Critical Care Medicine, Shengli Clinical Medical College of Fujian Medical University, Fujian Provincial Hospital , Fuzhou, Fujian 350001, China)
Material： Biomedicine & Pharmacotherapy  (Biomedicine and Pharmacotherapy)
Volume： 123  Page： Null  Publication year： 2020 
JST Material Number： A0845C  ISSN： 0753-3322  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Acute lung injury (ALI) is a c...

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Thesaurus term： *NF-kappaB ,  phosphorylation ,  human(primates) ,  inflammation ,  heme oxygenase ,  ER stress ,  *lipopolysaccharide ,  *oxidative stress ,  inflammatory cytokine ,  survival ratio ,  myeloperoxidase ,  lactate dehydrogenase ,  *endoplasmic reticulum ,  up-regulation ,  erythrocyte

Author keywords (5)： ALI ,  CRBN ,  Inflammation ,  Oxidative stress ,  ER stress

JST classification (2)： Basic research of pharmacology of crude drugs  (GX06020J) ,  Basic medicine on digestive system  (GH01020E)

Terms in the title (11)： ノックダウン ,  酸化ストレス ,  小胞体 ,  Er ,  ストレス ,  NF-κB ,  シグナル伝達 ,  リポ多糖類 ,  誘発 ,  急性肺損傷 ,  緩和