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J-GLOBAL ID：202002213843560039   Reference number：20A0614466

Poly(ethylene glycol) shell-sheddable TAT-modified core cross-linked nano-micelles: TAT-enhanced cellular uptake and lysosomal pH-triggered doxorubicin release

ポリ(エチレングリコール)シェル-シェーダブルTat修飾コア架橋ナノミセル:Tat増強細胞取り込みとリソソームpH誘発ドキソルビシン放出【JST・京大機械翻訳】

Author (7)： Zhang Yuliu (Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, School of Chemistry and Molecular Engineering, East China Normal University, Shanghai 200062, PR China) ,  Xiao Yi (Department of Radiology and Nuclear Medicine, Changzheng Hospital, Naval Medical University, Shanghai 200003, PR China) ,  Huang Yushu (Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, School of Chemistry and Molecular Engineering, East China Normal University, Shanghai 200062, PR China) ,  He Yang (Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, School of Chemistry and Molecular Engineering, East China Normal University, Shanghai 200062, PR China) ,  Xu Yanyun (Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, School of Chemistry and Molecular Engineering, East China Normal University, Shanghai 200062, PR China) ,  Lu Wei (Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, School of Chemistry and Molecular Engineering, East China Normal University, Shanghai 200062, PR China) ,  Yu Jiahui (Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, School of Chemistry and Molecular Engineering, East China Normal University, Shanghai 200062, PR China)
Material： Colloids and Surfaces. B. Biointerfaces  (Colloids Surf B Biointerfaces)
Volume： 188  Page： Null  Publication year： 2020 
JST Material Number： W0541A  ISSN： 0927-7765  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： This study aimed to develop sh...

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Thesaurus term： interaction ,  nanostructure ,  graft copolymer ,  oxidation-reduction reaction ,  aqueous solution ,  self assembly ,  drug release ,  drug delivery system ,  drug resistance ,  tumor ,  *lysosome ,  tumor cell ,  *micelle ,  hydrophobic ,  in vitro experiment

Author keywords (4)： TAT-modified ,  Enhanced endocytosis ,  Core cross-linked nanomicelles ,  Lysosomal pH-triggered doxorubicin release

JST classification (1)： Physical pharmacy  (GY01012A)

Terms in the title (15)： エチレングリコール ,  シェル ,  TAT ,  修飾 ,  コア ,  架橋 ,  ナノミセル ,  増強 ,  細胞 ,  取り込み ,  リソソーム ,  pH ,  誘発 ,  ドキソルビシン ,  放出