Art

J-GLOBAL ID：202002214317888958   Reference number：20A1373467

Amino Acid Profiling Study of Psidium guajava L. Leaves as an Effective Treatment for Type 2 Diabetic Rats

2型糖尿病ラットの有効な治療としてのPsidium guajava L.葉のアミノ酸プロファイリング研究【JST・京大機械翻訳】

Author (12)： Xu Chang ( Key Laboratory of Tropical Biological Resources of Ministry of Education, Department of Pharmaceutical Sciences, School of Life and Pharmaceutical Sciences, Hainan University, Haikou 570228, China) ,  Li Xin ( Key Laboratory of Tropical Biological Resources of Ministry of Education, Department of Pharmaceutical Sciences, School of Life and Pharmaceutical Sciences, Hainan University, Haikou 570228, China) ,  Zeng Debin ( Anning Hospital of Hainan Province, Haikou 570206, China) ,  Liu Ying ( Research Center for Drug Safety Evaluation of Hainan Province, Haikou 571199, China) ,  Gao Yuhang ( Key Laboratory of Tropical Biological Resources of Ministry of Education, Department of Pharmaceutical Sciences, School of Life and Pharmaceutical Sciences, Hainan University, Haikou 570228, China) ,  Tsunoda Makoto ( Graduate School of Pharmaceutical Sciences, The University of Tokyo, 7-3-1 Hongo, Bunkyoku, Tokyo 113-0033, Japan) ,  Deng Shiming ( Key Laboratory of Tropical Biological Resources of Ministry of Education, Department of Pharmaceutical Sciences, School of Life and Pharmaceutical Sciences, Hainan University, Haikou 570228, China) ,  Xie Xi ( Key Laboratory of Tropical Biological Resources of Ministry of Education, Department of Pharmaceutical Sciences, School of Life and Pharmaceutical Sciences, Hainan University, Haikou 570228, China) ,  Wang Rong ( Key Laboratory of Tropical Biological Resources of Ministry of Education, Department of Pharmaceutical Sciences, School of Life and Pharmaceutical Sciences, Hainan University, Haikou 570228, China) ,  Li Lu-shuang ( Key Laboratory of Tropical Biological Resources of Ministry of Education, Department of Pharmaceutical Sciences, School of Life and Pharmaceutical Sciences, Hainan University, Haikou 570228, China) ,  Song Yanting ( Key Laboratory of Tropical Biological Resources of Ministry of Education, Department of Pharmaceutical Sciences, School of Life and Pharmaceutical Sciences, Hainan University, Haikou 570228, China) ,  Zhang Yingxia ( Key Laboratory of Tropical Biological Resources of Ministry of Education, Department of Pharmaceutical Sciences, School of Life and Pharmaceutical Sciences, Hainan University, Haikou 570228, China)
Material： Evidence-Based Complementary and Alternative Medicine (Web)
Volume： 2020  Page： Null  Publication year： 2020 
JST Material Number： U7703A  ISSN： 1741-427X  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Abstract/Point： Type 2 diabetes mellitus (T2DM...

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Thesaurus term： biosynthesis ,  *amino acid ,  hypoglycemic action ,  metabolite ,  *diabetes mellitus ,  side effect ,  *rat ,  *Psidium guajava ,  metabolic error ,  metabolic pathway ,  hypoglycemia ,  principal component analysis ,  aliphatic amine ,  aliphatic carboxylic acid ,  branched-chain amino acid ,  sulfide(organic) ,  sulfur containing amino acid ,  primary amine ,  nitrogen heterocyclic compound ,  polynuclear aromatic compound

JST classification (2)： Basic research of drugs acting on carbohydrate metabolism  (GW13020Q) ,  Plant biochemistry  (EH01050J)

Substance index (3)： Leucine ,  Methionine ,  Tryptophan

Reference (21)：

• D. Yoriko, M. Kouji, "Anti-hyperglycemic and anti-hyperlipidemic effects of P. guajava L. leaf extract," Nutrition & Metabolism, vol. 7, no. 1, pp. 9, 2010.
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• N. M. Kaplan, "The deadly quartet," Archives of Internal Medicine, vol. 149, no. 7, pp. 1514-1520, 1989.
• D. R. Salvatore, A. Biagio, C. Eusebio et al., "Type 2 diabetes mellitus and cardiovascular disease: genetic and epigenetic links," Frontiers in Endocrinology, vol. 9, 2018.
• X.-h. Feng, Z.-h. Wang, D.-l. Meng, X. Li, "Cytotoxic and antioxidant constituents from the leaves of Psidium guajava," Bioorganic & Medicinal Chemistry Letters, vol. 25, no. 10, pp. 2193-2198, 2015.

Terms in the title (8)： 2型糖尿病 ,  ラット ,  治療 ,  Psidium ,  葉 ,  アミノ酸 ,  プロファイリング ,  研究