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J-GLOBAL ID：202002215309312511   Reference number：20A1350087

The HOIL-1L ligase modulates immune signalling and cell death via monoubiquitination of LUBAC

HOIL-1LリガーゼはLUBACのモノユビキチン化を介して免疫シグナリングと細胞死を調節する【JST・京大機械翻訳】

Author (14)： Fuseya Yasuhiro (Department of Molecular and Cellular Physiology, Graduate School of Medicine, Kyoto University, Kyoto, Japan) ,  Fuseya Yasuhiro (Department of Neurology, Graduate School of Medicine, Kyoto University Hospital, Kyoto, Japan) ,  Fujita Hiroaki (Department of Molecular and Cellular Physiology, Graduate School of Medicine, Kyoto University, Kyoto, Japan) ,  Kim Minsoo (Department of Molecular and Cellular Physiology, Graduate School of Medicine, Kyoto University, Kyoto, Japan) ,  Kim Minsoo (The Hakubi Center for Advanced Research, Kyoto University, Kyoto, Japan) ,  Ohtake Fumiaki (Laboratory of Protein Metabolism, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan) ,  Ohtake Fumiaki (Institute for Advanced Life Sciences, Hoshi University, Tokyo, Japan) ,  Nishide Akira (Department of Molecular and Cellular Physiology, Graduate School of Medicine, Kyoto University, Kyoto, Japan) ,  Nishide Akira (The Hakubi Center for Advanced Research, Kyoto University, Kyoto, Japan) ,  Sasaki Katsuhiro (Department of Molecular and Cellular Physiology, Graduate School of Medicine, Kyoto University, Kyoto, Japan) ,  Saeki Yasushi (Laboratory of Protein Metabolism, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan) ,  Tanaka Keiji (Laboratory of Protein Metabolism, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan) ,  Takahashi Ryosuke (Department of Neurology, Graduate School of Medicine, Kyoto University Hospital, Kyoto, Japan) ,  Iwai Kazuhiro (Department of Molecular and Cellular Physiology, Graduate School of Medicine, Kyoto University, Kyoto, Japan)
Material： Nature Cell Biology  (Nat Cell Biol)
Volume： 22  Issue： 6  Page： 663-673  Publication year： 2020 
JST Material Number： W1369A  ISSN： 1465-7392  Document type： Article
Article type： 原著論文  Country of issue： Germany, Federal Republic of (DEU)  Language： ENGLISH (EN)

Abstract/Point： Abstract: The linear ubiquitin...

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Thesaurus term： conjugation ,  substrate (biochemistry) ,  Dermatitis ,  *ligase ,  subunit ,  complex (substance) ,  Salmonella ,  *ubiquitin ,  immunologic deficiency syndrome ,  *Cell Death ,  pathogenesis ,  NF-kappaB ,  *Ubiquitination ,  *monoubiquitination ,  *LUBAC ,  microorganism

JST classification (1)： Biological function  (EB03040U)

Terms in the title (7)： リガーゼ ,  LUBAC ,  モノユビキチン化 ,  免疫 ,  シグナリング ,  細胞死 ,  調節