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J-GLOBAL ID：202002216277004549   Reference number：20A0126422

Microcystin exposure worsens nonalcoholic fatty liver disease associated ectopic glomerular toxicity via NOX-2-MIR21 axis

ミクロシスチン曝露は非アルコール性脂肪肝疾患関連異所性糸球体毒性をNOX-2-miR21軸を介して悪化させる【JST・京大機械翻訳】

Author (17)： Sarkar Sutapa (Environmental Health and Disease Laboratory, Department of Environmental Health Sciences, University of South Carolina, United States) ,  Sarkar Sutapa (NIEHS Center for Oceans and Human Health on Climate Change Interactions, Department of Environmental Health Sciences, University of South Carolina, United States) ,  Alhasson Firas (Environmental Health and Disease Laboratory, Department of Environmental Health Sciences, University of South Carolina, United States) ,  Kimono Diana (Environmental Health and Disease Laboratory, Department of Environmental Health Sciences, University of South Carolina, United States) ,  Kimono Diana (NIEHS Center for Oceans and Human Health on Climate Change Interactions, Department of Environmental Health Sciences, University of South Carolina, United States) ,  Albadrani Muayad (Environmental Health and Disease Laboratory, Department of Environmental Health Sciences, University of South Carolina, United States) ,  Albadrani Muayad (NIEHS Center for Oceans and Human Health on Climate Change Interactions, Department of Environmental Health Sciences, University of South Carolina, United States) ,  Seth Ratanesh K. (Environmental Health and Disease Laboratory, Department of Environmental Health Sciences, University of South Carolina, United States) ,  Seth Ratanesh K. (NIEHS Center for Oceans and Human Health on Climate Change Interactions, Department of Environmental Health Sciences, University of South Carolina, United States) ,  Xiao Shuo (NIEHS Center for Oceans and Human Health on Climate Change Interactions, Department of Environmental Health Sciences, University of South Carolina, United States) ,  Porter Dwayne E. (NIEHS Center for Oceans and Human Health on Climate Change Interactions, Department of Environmental Health Sciences, University of South Carolina, United States) ,  Scott Geoff I. (NIEHS Center for Oceans and Human Health on Climate Change Interactions, Department of Environmental Health Sciences, University of South Carolina, United States) ,  Brooks Bryan (Department of Environmental Science, Baylor University, United States) ,  Nagarkatti Mitzi (Pathology, Microbiology and Immunology, University of South Carolina School of Medicine, United States) ,  Nagarkatti Prakash (Pathology, Microbiology and Immunology, University of South Carolina School of Medicine, United States) ,  Chatterjee Saurabh (Environmental Health and Disease Laboratory, Department of Environmental Health Sciences, University of South Carolina, United States) ,  Chatterjee Saurabh (NIEHS Center for Oceans and Human Health on Climate Change Interactions, Department of Environmental Health Sciences, University of South Carolina, United States)
Material： Environmental Toxicology and Pharmacology  (Environ Toxicol Pharmacol)
Volume： 73  Page： Null  Publication year： 2020 
JST Material Number： W0413B  ISSN： 1382-6689  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： NAFLD often results in cardiov...

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Thesaurus term： cytokine ,  complication ,  cultured cell ,  cicatrix ,  *nitrogen oxide ,  up-regulation ,  incubate ,  glomerulonephritis ,  oxidative stress ,  inflammation ,  cardiovascular system ,  inflammatory cytokine ,  extracellular matrix ,  mesangium cell
Semi thesaurus term： 糸球体間質 , 【Automatic Indexing@JST】

Author keywords (8)： Leptin ,  NOX-2 ,  NADPH ,  Mesangial cells ,  miR21 ,  Oxidative stress ,  NAFLD ,  JAK/STAT

JST classification (2)： Toxicity of organic compounds  (GZ02030Y) ,  Basic medicine on digestive system  (GH01020E)

Terms in the title (8)： ミクロシスチン ,  曝露 ,  非アルコール性脂肪肝疾患 ,  異所性 ,  糸球体 ,  毒性 ,  NOX ,  悪化