Art

J-GLOBAL ID：202002216319410734   Reference number：20A2435410

Telmisartan Exacerbates Cisplatin-Induced Nephrotoxicity in a Mouse Model

テルミサルタンはマウスモデルにおいてシスプラチン誘発腎毒性を悪化させる

Author (8)： Hosoda Atsuki (Department of Pathological Biochemistry, Faculty of Pharmaceutical Sciences, Setsunan University) ,  Hosoda Atsuki (Department of Pharmacy, National Hospital Organization, Osaka Minami Medical Center) ,  Matsumoto Yoshio (Department of Pathological Biochemistry, Faculty of Pharmaceutical Sciences, Setsunan University) ,  Toriyama Yuuki (Department of Pathological Biochemistry, Faculty of Pharmaceutical Sciences, Setsunan University) ,  Tsuji Takumi (Department of Pathological Biochemistry, Faculty of Pharmaceutical Sciences, Setsunan University) ,  Yoshida Yuya (Department of Pathological Biochemistry, Faculty of Pharmaceutical Sciences, Setsunan University) ,  Masamichi Shuji (Department of Pharmacy, National Hospital Organization, Osaka Minami Medical Center) ,  Kohno Takeyuki (Department of Pathological Biochemistry, Faculty of Pharmaceutical Sciences, Setsunan University)
Material： Biological and Pharmaceutical Bulletin (Web)
Volume： 43  Issue： 9  Page： 1331-1337(J-STAGE)  Publication year： 2020 
JST Material Number： U1402A  ISSN： 1347-5215  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *cisplatin ,...
Semi thesaurus term： *RAS inhibitors ,...

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Author keywords (10)： cisplatin ,  nephrotoxicity ,  telmisartan ,  renin angiotensin system inhibitor ,  fibrosis ,  cisplatin ,  nephrotoxicity ,  telmisartan ,  renin angiotensin system inhibitor ,  fibrosis

JST classification (3)： Basic research of antitumor(=antineoplastic)drugs  (GW16010A) ,  Basic medicine on cardiovascular system  (GJ01020K) ,  Poisoning in general  (GD06010Q)

Substance index (3)： Amlodipine ,  Enalapril ,  Telmisartan

Reference (19)：

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• 2) Latcha S, Jaimes EA, Patil S, Glezerman IG, Mehta S, Flombaum CD. Long-term renal outcomes after cisplatin treatment. Clin. J. Am. Soc. Nephrol., 11, 1173-1179 (2016).
• 3) Luke DR, Vadiei K, Lopez-Berestein G. Role of vascular congestion in cisplatin-induced acute renal failure in the rat. Nephrol. Dial. Transplant., 7, 1-7 (1992).
• 4) Komaki K, Kusaba T, Tanaka M, Kado H, Shiotsu Y, Matsui M, Shiozaki A, Nakano H, Ishikawa T, Fujiwara H, Konishi H, Itoh Y, Matoba S. Lower blood pressure and risk of cisplatin nephrotoxicity: a retrospective cohort study. BMC Cancer, 17, 144 (2017).
• 5) Saleh S, Ain-Shoka AA, El-Demerdash E, Khalef MM. Protective effects of the angiotensin II receptor blocker losartan on cisplatin-induced kidney injury. Chemotherapy, 55, 399-406 (2009).

Terms in the title (6)： テルミサルタン ,  マウスモデル ,  シスプラチン ,  誘発 ,  腎毒性 ,  悪化