Art

J-GLOBAL ID：202002216506072157   Reference number：20A0201648

A Trans-amplifying RNA Vaccine Strategy for Induction of Potent Protective Immunity

強力な防御免疫の誘導のためのトランス増幅RNAワクチン戦略【JST・京大機械翻訳】

Author (13)： Beissert Tim (TRON (Translational Oncology at the University Medical Center), Johannes Gutenberg University Mainz, Mainz, Germany) ,  Perkovic Mario (TRON (Translational Oncology at the University Medical Center), Johannes Gutenberg University Mainz, Mainz, Germany) ,  Vogel Annette (BioNTech AG, Mainz, Germany) ,  Erbar Stephanie (BioNTech AG, Mainz, Germany) ,  Walzer Kerstin C. (BioNTech AG, Mainz, Germany) ,  Hempel Tina (TRON (Translational Oncology at the University Medical Center), Johannes Gutenberg University Mainz, Mainz, Germany) ,  Brill Silke (TRON (Translational Oncology at the University Medical Center), Johannes Gutenberg University Mainz, Mainz, Germany) ,  Haefner Erik (Department for Internal Medicine, Johannes Gutenberg University Mainz, Mainz, Germany) ,  Becker Rene (TRON (Translational Oncology at the University Medical Center), Johannes Gutenberg University Mainz, Mainz, Germany) ,  Tuereci OEzlem (BioNTech AG, Mainz, Germany) ,  Sahin Ugur (TRON (Translational Oncology at the University Medical Center), Johannes Gutenberg University Mainz, Mainz, Germany) ,  Sahin Ugur (BioNTech AG, Mainz, Germany) ,  Sahin Ugur (Department for Internal Medicine, Johannes Gutenberg University Mainz, Mainz, Germany)
Material： Molecular Therapy  (Mol Ther)
Volume： 28  Issue： 1  Page： 119-128  Publication year： 2020 
JST Material Number： W1762A  ISSN： 1525-0016  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Here, we present a potent RNA ...

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Thesaurus term： hemagglutination ,  *RNA ,  mRNA ,  RNA replicase ,  antigen ,  alphavirus ,  influenza vaccine ,  adaptability ,  neutralizing antibody ,  replicon ,  influenza ,  vector(genetics) ,  production process(control) ,  optimization ,  *vaccine

Author keywords (8)： vaccine ,  RNA vaccine ,  saRNA ,  taRNA ,  alphavirus ,  influenza vaccine ,  trans-replication ,  replicon

JST classification (4)： Gene expression  (EC02040Q) ,  Basic neurology  (GN01020W) ,  Gene manipulation  (EC02050B) ,  Cell physiology in general  (EF02010S)

Terms in the title (7)： 防御免疫 ,  誘導 ,  トランス ,  増幅 ,  RNA ,  ワクチン ,  戦略