Art

J-GLOBAL ID：202002216683701857   Reference number：20A0673261

Butyrate protects against high-fat diet-induced atherosclerosis via up-regulating ABCA1 expression in apolipoprotein E-deficiency mice

酪酸はアポリポ蛋白質E欠損マウスにおいてABCA1発現をアップレギュレートすることにより高脂肪食誘発性アテローム性動脈硬化症から保護する【JST・京大機械翻訳】

Author (11)： Du Yu (NHC Key Laboratory of Biotechnology of Antibiotics, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China) ,  Li Xingxing (NHC Key Laboratory of Biotechnology of Antibiotics, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China) ,  Li Xingxing (CAMS Key Laboratory of Synthetic Biology for Drug Innovation, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China) ,  Su Chunyan (NHC Key Laboratory of Biotechnology of Antibiotics, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China) ,  Xi Mei (NHC Key Laboratory of Biotechnology of Antibiotics, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China) ,  Zhang Xiumin (NHC Key Laboratory of Biotechnology of Antibiotics, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China) ,  Jiang Zhibo (NHC Key Laboratory of Biotechnology of Antibiotics, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China) ,  Jiang Zhibo (CAMS Key Laboratory of Synthetic Biology for Drug Innovation, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China) ,  Wang Li (NHC Key Laboratory of Biotechnology of Antibiotics, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China) ,  Hong Bin (NHC Key Laboratory of Biotechnology of Antibiotics, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China) ,  Hong Bin (CAMS Key Laboratory of Synthetic Biology for Drug Innovation, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China)
Material： British Journal of Pharmacology  (Br J Pharmacol)
Volume： 177  Issue： 8  Page： 1754-1772  Publication year： 2020 
JST Material Number： B0334A  ISSN： 0007-1188  CODEN： BJPCB  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Abstract/Point： BACKGROUND AND PURPOSE: The gu...

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Thesaurus term： *atherosclerosis ,  lipid ,  in vitro experiment ,  *apo E ,  microorganism ,  up-regulation ,  Western blotting ,  gene silencing ,  gene ,  enteric microbe ,  weight gain ,  gene expression ,  *high fat diet ,  macrophage ,  fatty liver

JST classification (1)： Basic medicine on cardiovascular system  (GJ01020K)

Terms in the title (8)： 酪酸 ,  アポリポ蛋白質E ,  欠損 ,  マウス ,  ABCA1 ,  発現 ,  高脂肪食 ,  アテローム性動脈硬化症