Art

J-GLOBAL ID：202002217074776769   Reference number：20A0456406

MPMBP down-regulates Toll-like receptor (TLR) 2 ligand-induced proinflammatory cytokine production by inhibiting NF-κB but not AP-1 activation

MPMBPは,AP-1活性化ではなく,NF-κBを阻害することによりToll様受容体(TLR)2リガンド誘導炎症誘発性サイトカイン産生を下方制御する【JST・京大機械翻訳】

Author (4)： Tamai Riyoko (Department of Oral Medical Science, Ohu University School of Dentistry, 31-1 Misumido, Tomitamachi, Koriyama, Fukushima 963-8611, Japan) ,  Suzuki Keiko (Department of Pharmacology, School of Dentistry, Showa University, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo 142-8555, Japan) ,  Mashima Izumi (Department of Oral Medical Science, Ohu University School of Dentistry, 31-1 Misumido, Tomitamachi, Koriyama, Fukushima 963-8611, Japan) ,  Kiyoura Yusuke (Department of Oral Medical Science, Ohu University School of Dentistry, 31-1 Misumido, Tomitamachi, Koriyama, Fukushima 963-8611, Japan)
Material： International Immunopharmacology  (Int Immunopharmacol)
Volume： 79  Page： Null  Publication year： 2020 
JST Material Number： T0026B  ISSN： 1567-5769  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： MPMBP is a novel non-nitrogen-...

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Thesaurus term： *NF-kappaB ,  antioxidation ,  *AP-1 transcription factor ,  bone resorption ,  side chain ,  *Toll like receptor ,  translocation(genetics) ,  TNF alpha ,  *inflammatory cytokine ,  cytotoxicity ,  chemokine ,  *down-regulation ,  incubate ,  lipid ,  p38 MAP kinase

Author keywords (6)： Non-NBPs ,  MPMBP ,  TLR ,  Proinflammatory cytokines ,  NF-κB ,  AP-1

JST classification (3)： Basic research of immunotherapeutic agents and blood preparations  (GW22010D) ,  Biophylaxis and immune systems in general  (ED01010F) ,  Cell physiology in general  (EF02010S)

Terms in the title (10)： AP-1 ,  活性化 ,  NF-κB ,  阻害 ,  Toll様受容体 ,  TLR ,  リガンド ,  誘導 ,  炎症誘発性サイトカイン ,  下方制御