Art

J-GLOBAL ID：202002217538724650   Reference number：20A1092590

Preoperative growth hormone (GH) peak values during a GH releasing peptide-2 test reflect the severity of hypopituitarism and the postoperative recovery of GH secretion in patients with non-functioning pituitary adenomas

非機能性下垂体腺腫患者における成長ホルモン(GH)放出ペプチド2試験での術前GHピーク値は機能低下症の重症度およびGH分泌の術後回復を反映する

Author (6)： Soga Akimi (Department of Endocrinology, Diabetes and Metabolism, Graduate School of Medicine, Nippon Medical School, Tokyo 113-8603, Japan) ,  Fukuda Izumi (Department of Endocrinology, Diabetes and Metabolism, Graduate School of Medicine, Nippon Medical School, Tokyo 113-8603, Japan) ,  Kobayashi Shunsuke (Department of Endocrinology, Diabetes and Metabolism, Graduate School of Medicine, Nippon Medical School, Tokyo 113-8603, Japan) ,  Tahara Shigeyuki (Department of Neurosurgery, Graduate School of Medicine, Nippon Medical School, Tokyo 113-8603, Japan) ,  Morita Akio (Department of Neurosurgery, Graduate School of Medicine, Nippon Medical School, Tokyo 113-8603, Japan) ,  Sugihara Hitoshi (Department of Endocrinology, Diabetes and Metabolism, Graduate School of Medicine, Nippon Medical School, Tokyo 113-8603, Japan)
Material： Endocrine Journal (Web)
Volume： 67  Issue： 2  Page： 167-175(J-STAGE)  Publication year： 2020 
JST Material Number： U1479A  ISSN： 1348-4540  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： human(primates) ,...
Semi thesaurus term： Disease severity ,...

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Author keywords (4)： GH releasing peptide (GHRP)-2 test ,  Non-functioning pituitary adenomas (NFPA) ,  Adult growth hormone deficiency ,  Hypopituitarism

JST classification (2)： Clinical oncology in general  (GE03010Y) ,  Tumors(=neoplasms)of endocrine system  (GL04000P)

Substance index (1)： KP-102

Reference (15)：

• 1 Carroll PV, Christ ER, Bengtsson BA, Carlsson L, Christiansen JS, et al. (1998) Growth Hormone deficiency in adulthood and the effects of growth hormone replacement: a review. Growth Hormone Research Society Scientific Committee. J Clin Endocrinol Metab 83: 382-395.
• 2 Takahashi Y (2017) The role of growth hormone and insulin-like growth factor-I in the liver. Int J Mol Sci 18: 1447.
• 3 Irie M, Itoh Y, Miyashita Y, Tsushima T, Shirai K (2004) Complication in adults with growth hormone deficiency-A Survey study in Japan. Endocr J 51: 479-485.
• 4 Snyder PJ (2018) Growth hormone deficiency in adults. In: UpToDate, Post TW, Ed, UpToDate. Waltham, MA. https: //www.uptodate.com (Accessed on January 30, 2019.)
• 5 Chihara K, Shimatsu A, Hizuka N, Tanaka T, Seino Y, et al. (2007) A simple diagnostic test using GH-releasing peptide-2 in adult GH deficiency. Eur J Endocrinol 157: 19-27.

Terms in the title (13)： 非機能性下垂体腺腫 ,  患者 ,  成長ホルモン ,  GH ,  放出 ,  ペプチド ,  試験 ,  術前 ,  ピーク値 ,  機能低下 ,  重症度 ,  分泌 ,  回復