Art

J-GLOBAL ID：202002218301909693   Reference number：20A2540050

Triterpenoid Saponin AG8 from Ardisia gigantifolia stapf. Induces Triple Negative Breast Cancer Cells Apoptosis through Oxidative Stress Pathway

Ardisia gigantifolia stapfからのトリテルペノイドサポニンAG8は酸化ストレス経路を通してトリプルネガティブ乳癌細胞アポトーシスを誘導する【JST・京大機械翻訳】

Author (8)： Mu Li-Hua (Department of Clinical Pharmacology, The Medical Supplies Center, Chinese PLA General Hospital, Beijing 100853, China) ,  Wang Li-Hua (Department of Clinical Pharmacology, The Medical Supplies Center, Chinese PLA General Hospital, Beijing 100853, China) ,  Yu Teng-Fei (Department of Ultrasound, Beijing Tiantan Hospital of Capital Medical University, Beijing 100050, China) ,  Wang Yu-Ning (Clinical Surgery Division, The First Medical Center, Chinese PLA General Hospital, Beijing 100853, China) ,  Yan Hong (Department of Obstetrics and Gynecology, The First Medical Center, Chinese PLA General Hospital, Beijing 100853, China) ,  Liu Ping (Department of Clinical Pharmacology, The Medical Supplies Center, Chinese PLA General Hospital, Beijing 100853, China) ,  Yan Can (Department of Basic Theory of Chinese Medicine, School of Pre-Clinical Medicine, Guangzhou University of Chinese Medicine, Guangzhou 510060, China) ,  Yan Can (The Research Centre of Basic Integrative Medicine, Guangzhou University of Chinese Medicine, Guangzhou 510060, China)
Material： Oxidative Medicine and Cellular Longevity (Web)  (Oxidative Med Cell Longev (Web))
Volume： 2020  Page： Null  Publication year： 2020 
JST Material Number： U7012A  ISSN： 1942-0900  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Abstract/Point： Triple-negative breast cancers...

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Thesaurus term： antitumor action ,  cytochrome c ,  human(primates) ,  mitochondria ,  phosphorylation ,  survival ratio ,  cytotoxicity ,  mesenchyme ,  *apoptosis ,  EGF receptor ,  progesterone receptor ,  estrogen receptor ,  *oxidative stress
Semi thesaurus term： MDA-MB-231細胞 ,  *トリプルネガティブ乳癌 , 【Automatic Indexing@JST】

JST classification (1)： Cell physiology in general  (EF02010S)

Reference (46)：

• V. S. Jamdade, N. Sethi, N. A. Mundhe, P. Kumar, M. Lahkar, N. Sinha, "Therapeutic targets of triple-negative breast cancer: a review," British Journal of Pharmacology, vol. 172, no. 17, pp. 4228-4237, 2015.
• G. J. Morris, S. Naidu, A. K. Topham, F. Guiles, Y. Xu, P. McCue, G. F. Schwartz, P. K. Park, A. L. Rosenberg, K. Brill, E. P. Mitchell, "Differences in breast carcinoma characteristics in newly diagnosed African-American and Caucasian patients," Cancer, vol. 110, no. 4, pp. 876-884, 2007.
• T. Ovcaricek, S. Frkovic, E. Matos, B. Mozina, S. Borstnar, "Triple negative breast cancer - prognostic factors and survival," Radiology and Oncology, vol. 45, no. 1, pp. 46-52, 2011.
• M. B. Chougule, A. R. Patel, T. Jackson, M. Singh, "Antitumor activity of Noscapine in combination with Doxorubicin in triple negative breast cancer," PLoS One, vol. 6, no. 3, article e17733, 2011.
• G. von Minckwitz, M. Martin, "Neoadjuvant treatments for triple-negative breast cancer (TNBC)," Annals of Oncology, vol. 23, no. 6, pp. vi35-vi39, 2012.

Terms in the title (7)： Ardisia ,  トリテルペノイドサポニン ,  酸化ストレス ,  経路 ,  トリプルネガティブ乳癌 ,  細胞アポトーシス ,  誘導