Art

J-GLOBAL ID：202002219755041574   Reference number：20A0450838

Maternal administration of tadalafil improves fetal ventricular systolic function in a Hey2 knockout mouse model of fetal heart failure

タダラフィルの母体投与は胎児心不全のHey2ノックアウトマウスモデルにおける胎児心室収縮機能を改善する【JST・京大機械翻訳】

Author (11)： Miyoshi Takekazu (Department of Regenerative Medicine and Tissue Engineering, National Cerebral and Cardiovascular Center Research Institute, Suita, Japan) ,  Miyoshi Takekazu (Department of Management and Strategy, Clinical Research Center, National Center for Child Health and Development, Tokyo, Japan) ,  Hisamitsu Takashi (Department of Molecular Physiology, National Cerebral and Cardiovascular Center Research Institute, Suita, Japan) ,  Ishibashi-Ueda Hatsue (Department of Pathology, National Cerebral and Cardiovascular Center Research Institute, Suita, Japan) ,  Ikemura Kenji (Department of Pharmacy, Mie University Hospital, Tsu, Japan) ,  Ikeda Tomoaki (Department of Obstetrics and Gynecology, Mie University Hospital, Tsu, Japan) ,  Miyazato Mikiya (Department of Biochemistry, National Cerebral and Cardiovascular Center Research Institute, Suita, Japan) ,  Kangawa Kenji (Department of Biochemistry, National Cerebral and Cardiovascular Center Research Institute, Suita, Japan) ,  Watanabe Yusuke (Department of Molecular Physiology, National Cerebral and Cardiovascular Center Research Institute, Suita, Japan) ,  Nakagawa Osamu (Department of Molecular Physiology, National Cerebral and Cardiovascular Center Research Institute, Suita, Japan) ,  Hosoda Hiroshi (Department of Regenerative Medicine and Tissue Engineering, National Cerebral and Cardiovascular Center Research Institute, Suita, Japan)
Material： International Journal of Cardiology  (Int J Cardiol)
Volume： 302  Page： 110-116  Publication year： 2020 
JST Material Number： A1233A  ISSN： 0167-5273  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： There is no established transp...

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Thesaurus term： *heart ventricle ,  Mitral Valve ,  HF ,  Uterus ,  Placenta ,  *Fetus ,  ultrasonic image ,  Phenotype ,  wild type ,  umbilical artery ,  *cardiac insufficiency ,  fetal therapy ,  filler (pharmaceuticals) ,  Left ventricle ,  *mouse model

Author keywords (6)： Congenital heart defect ,  Fetal therapy ,  Heart failure ,  High-frequency ultrasound imaging ,  Mouse ,  Tadalafil

JST classification (2)： Cardiovascular system diseases  (GJ03000C) ,  Treatment for cardiovasular system diseases in general  (GJ05010B)

Terms in the title (8)： タダラフィル ,  母体投与 ,  胎児心不全 ,  ノックアウトマウス ,  モデル ,  胎児 ,  心室 ,  収縮機能