Art

J-GLOBAL ID：202002219882201599   Reference number：20A1355532

Lipopolysaccharide-Deficient Acinetobacter baumannii Due to Colistin Resistance Is Killed by Neutrophil-Produced Lysozyme

コリスチン耐性によるリポ多糖欠損Acinetobacter baumanniiは好中球産生リゾチームにより殺菌される【JST・京大機械翻訳】

Author (17)： Kamoshida Go (Department of Microbiology and Infection Control Sciences, Kyoto Pharmaceutical University, Kyoto, Japan) ,  Kamoshida Go (Department of Microbiology and Immunology, School of Medicine, Teikyo University, Tokyo, Japan) ,  Akaji Takuya (Department of Microbiology and Immunology, School of Medicine, Teikyo University, Tokyo, Japan) ,  Takemoto Norihiko (Pathogenic Microbe Laboratory, Department of Infectious Diseases, Research Institute, National Center for Global Health and Medicine, Tokyo, Japan) ,  Suzuki Yusuke (Department of Microbiology and Immunology, School of Medicine, Teikyo University, Tokyo, Japan) ,  Sato Yoshinori (Department of Microbiology and Immunology, School of Medicine, Teikyo University, Tokyo, Japan) ,  Kai Daichi (Department of Microbiology and Infection Control Sciences, Kyoto Pharmaceutical University, Kyoto, Japan) ,  Hibino Taishi (Department of Microbiology and Infection Control Sciences, Kyoto Pharmaceutical University, Kyoto, Japan) ,  Yamaguchi Daiki (Department of Microbiology and Infection Control Sciences, Kyoto Pharmaceutical University, Kyoto, Japan) ,  Kikuchi-Ueda Takane (Department of Microbiology and Immunology, School of Medicine, Teikyo University, Tokyo, Japan) ,  Nishida Satoshi (Department of Microbiology and Immunology, School of Medicine, Teikyo University, Tokyo, Japan) ,  Unno Yuka (Department of Microbiology and Immunology, School of Medicine, Teikyo University, Tokyo, Japan) ,  Tansho-Nagakawa Shigeru (Department of Microbiology and Immunology, School of Medicine, Teikyo University, Tokyo, Japan) ,  Ubagai Tsuneyuki (Department of Microbiology and Immunology, School of Medicine, Teikyo University, Tokyo, Japan) ,  Miyoshi-Akiyama Tohru (Pathogenic Microbe Laboratory, Department of Infectious Diseases, Research Institute, National Center for Global Health and Medicine, Tokyo, Japan) ,  Oda Masataka (Department of Microbiology and Infection Control Sciences, Kyoto Pharmaceutical University, Kyoto, Japan) ,  Ono Yasuo (Department of Microbiology and Immunology, School of Medicine, Teikyo University, Tokyo, Japan)
Material： Frontiers in Microbiology (Web)
Volume： 11  Page： 573  Publication year： 2020 
JST Material Number： U7080A  ISSN： 1664-302X  Document type： Article
Article type： 原著論文  Country of issue： Switzerland (CHE)  Language： ENGLISH (EN)

Abstract/Point： Acinetobacter baumannii causes...

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Thesaurus term： polypeptide ,  Inflammation ,  antibacterial drug ,  antimicrobial action ,  *lysozyme ,  *lipopolysaccharide ,  Gram-Negative Bacteria ,  hospital infection ,  *Neutrophils ,  wild type ,  multiple drug resistance ,  *Acinetobacter baumannii ,  cytokine production ,  *Acinetobacter ,  *microorganism ,  *Neisseriaceae
Semi thesaurus term： *Acinetobacter ,  *コリスチン , 【Automatic Indexing@JST】

Author keywords (5)： Acinetobacter baumannii ,  colistin ,  LPS ,  lysozyme ,  neutrophil

JST classification (2)： Infectious diseases,parasitics diseases in general.  (GD01010H) ,  Physiology and pathogenicity of microbial infection  (EG03053T)

Reference (56)：

• Adams M. D., Nickel G. C., Bajaksouzian S., Lavender H., Murthy A. R., Jacobs M. R., et al (2009). Resistance to colistin in Acinetobacter baumannii associated with mutations in the PmrAB two-component system. Antimicrob. Agents Chemother. 53 3628-3634. doi: 10.1128/aac.00284-09
• Beceiro A., Llobet E., Aranda J., Bengoechea J. A., Doumith M., Hornsey M., et al (2011). Phosphoethanolamine modification of lipid A in colistin-resistant variants of Acinetobacter baumannii mediated by the pmrAB two-component regulatory system. Antimicrob. Agents Chemother. 55 3370-3379. doi: 10.1128/aac.00079-11
• Beceiro A., Moreno A., Fernandez N., Vallejo J. A., Aranda J., Adler B., et al (2014). Biological cost of different mechanisms of colistin resistance and their impact on virulence in Acinetobacter baumannii. Antimicrob. Agents Chemother. 58 518-526. doi: 10.1128/aac.01597-13
• Boll J. M., Crofts A. A., Peters K., Cattoir V., Vollmer W., Davies B. W., et al (2016). A penicillin-binding protein inhibits selection of colistin-resistant, lipooligosaccharide-deficient Acinetobacter baumannii. Proc. Natl. Acad. Sci. U.S.A. 113 E6228-E6237. doi: 10.1128/aac.01597-13
• Borregaard N., Sorensen O. E., Theilgaard-Monch K. (2007). Neutrophil granules: a library of innate immunity proteins. Trends Immunol. 28 340-345. doi: 10.1016/j.it.2007.06.002

Terms in the title (8)： コリスチン ,  耐性 ,  リポ多糖 ,  欠損 ,  Acinetobacter ,  好中球 ,  リゾチーム ,  殺菌