Art

J-GLOBAL ID：202002219908892632   Reference number：20A0672793

Amorphous solid dispersions containing residual crystallinity: Influence of seed properties and polymer adsorption on dissolution performance

残留結晶性を含む非晶質固体分散:溶解性能に及ぼすシード特性と高分子吸着の影響【JST・京大機械翻訳】

Author (4)： Moseson Dana E. (Department of Industrial and Physical Pharmacy, College of Pharmacy, Purdue University, West Lafayette, IN 47907, United States) ,  Parker Andrew S. (Charles D. Davidson School of Chemical Engineering, College of Engineering, Purdue University, West Lafayette, IN 47907, United States) ,  Beaudoin Stephen P. (Charles D. Davidson School of Chemical Engineering, College of Engineering, Purdue University, West Lafayette, IN 47907, United States) ,  Taylor Lynne S. (Department of Industrial and Physical Pharmacy, College of Pharmacy, Purdue University, West Lafayette, IN 47907, United States)
Material： European Journal of Pharmaceutical Sciences  (Eur J Pharm Sci)
Volume： 146  Page： Null  Publication year： 2020 
JST Material Number： W0673A  ISSN： 0928-0987  CODEN： EPSCED  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： The solubility advantage of am...

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Thesaurus term： solubility(ratio) ,  polymer crystal ,  *amorphous state ,  dissolution test ,  growth inhibition ,  atomic force microscope ,  *crystallinity ,  scanning electron microscope ,  *dissolution ,  risk factor ,  *crystal ,  nucleation ,  crystal growth ,  seed crystal ,  supersaturation

Author keywords (6)： Amorphous solid dispersion ,  Non-sink dissolution ,  Supersaturation ,  Crystal growth ,  Residual crystallinity ,  Polymer adsorption

JST classification (2)： Physicochemical characteristics of drugs  (GV01060M) ,  Solid preparations  (GY02030V)

Terms in the title (4)： 残留 ,  結晶性 ,  溶解 ,  高分子吸着