Art

J-GLOBAL ID：202002223177031549   Reference number：20A0665056

IL-2/IL-2 Receptor Pathway Plays a Crucial Role in the Growth and Malignant Transformation of HTLV-1-Infected T Cells to Develop Adult T-Cell Leukemia

IL-2/IL-2受容体経路は成人T細胞白血病を発症させるためにHTLV-1感染T細胞の増殖と悪性形質転換に重要な役割を果たす【JST・京大機械翻訳】

Author (12)： Maeda Michiyuki (Laboratory of Virus Control, Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto, Japan) ,  Tanabe-Shibuya Junko (Laboratory of Virus Control, Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto, Japan) ,  Miyazato Paola (Laboratory of Virus Control, Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto, Japan) ,  Miyazato Paola (Center for AIDS Research, School of Medicine, Kumamoto University, Kumamoto, Japan) ,  Masutani Hiroshi (Laboratory of Infection and Prevention, Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto, Japan) ,  Masutani Hiroshi (Department of Clinical Laboratory Sciences, Tenri Health Care University, Tenri, Japan) ,  Yasunaga Jun-ichirou (Laboratory of Virus Control, Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto, Japan) ,  Yasunaga Jun-ichirou (Institute for Advancement for Clinical and Translational Science, Kyoto University Hospital, Kyoto University, Kyoto, Japan) ,  Usami Kazumasa (Taigenkai Hospital, Ichinomiya, Japan) ,  Shimizu Akira (Institute for Advancement for Clinical and Translational Science, Kyoto University Hospital, Kyoto University, Kyoto, Japan) ,  Matsuoka Masao (Laboratory of Virus Control, Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto, Japan) ,  Matsuoka Masao (Department of Hematology, School of Medicine, Kumamoto University, Kumamoto, Japan)
Material： Frontiers in Microbiology (Web)
Volume： 11  Page： 356  Publication year： 2020 
JST Material Number： U7080A  ISSN： 1664-302X  Document type： Article
Article type： 原著論文  Country of issue： Switzerland (CHE)  Language： ENGLISH (EN)

Abstract/Point： T cells infected with human T-...

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Thesaurus term： p53 protein ,  HTLV ,  tumor ,  interleukin ,  CD25 antigen ,  response characteristic ,  *T cell ,  *HTLV1 ,  *interleukin 2 ,  gene ,  tumor cell ,  *adult T cell leukemia ,  receptor ,  *leukemia
Semi thesaurus term： ATL細胞 , 【Automatic Indexing@JST】

Author keywords (7)： adult T-cell leukemia ,  human T-cell leukemia virus type 1 ,  IL-2/IL-15/IL-2R ,  Tax ,  HBZ ,  p53 ,  growth progression

JST classification (2)： Blood cell tumors(=neoplasms)  (GK04000M) ,  Carcinogenic mechanisms and factors  (GE02020C)

Reference (50)：

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• Gallo R. C. (2005). The discovery of the first human retrovirus: HTLV-1 and HTLV-2. Retrovirology 2:17. doi: 10.1038/leu.2010.286

Terms in the title (11)： IL-2 ,  受容体 ,  経路 ,  成人T細胞白血病 ,  発症 ,  HTLV-1 ,  感染 ,  T細胞 ,  増殖 ,  悪性形質転換 ,  役割