Art

J-GLOBAL ID：202002223917834968   Reference number：20A1015361

Analysis of the association between resolution of disseminated intravascular coagulation (DIC) and treatment outcomes in post-marketing surveillance of thrombomodulin alpha for DIC with infectious disease and with hematological malignancy by organ failure

感染症を伴うDICおよび臓器不全による血液悪性腫瘍に対するトロンボモジュリンαの市販後監視における播種性血管内凝固(DIC)と治療転帰の間の関連性の分析【JST・京大機械翻訳】

Author (11)： Kawano Noriaki (Department of Internal Medicine, Miyazaki Prefectural Miyazaki Hospital, Miyazaki, Japan) ,  Wada Hideo (Department of General Medicine, Mie Prefectural General Medical Center, Mie, Japan) ,  Uchiyama Toshimasa (Department of Laboratory Medicine, National Hospital Organization Takasaki General Medical Center, Gunma, Japan) ,  Kawasugi Kazuo (Faculty of Medical Technology, Teikyo University, Tokyo, Japan) ,  Madoiwa Seiji (Department of Clinical Laboratory Medicine, Tokyo Saiseikai Central Hospital, Tokyo, Japan) ,  Takezako Naoki (Department of Hematology, National Hospital Organization Disaster Medical Center, Tokyo, Japan) ,  Suzuki Kei (Emergency and Critical Care Center, Mie University Hospital, Mie, Japan) ,  Seki Yoshinobu (Department of Hematology, Uonuma Institute of Community Medicine, Niigata University Medical and Dental Hospital, Niigata, Japan) ,  Ikezoe Takayuki (Department of Hematology, Fukushima Medical University, Fukushima, Japan) ,  Hattori Tsuyoshi (Department of Medical Affairs, Asahi Kasei Pharma Corporation, Tokyo, Japan) ,  Okamoto Kohji (Department of Surgery, Center for Gastroenterology and Liver Disease, Kitakyushu City Yahata Hospital, Fukuoka, Japan)
Material： Thrombosis Journal (Web)
Volume： 18  Issue： 1  Page： 1-9  Publication year： 2020 
JST Material Number： U7553A  ISSN： 1477-9560  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Abstract/Point： Although disseminated intravas...

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Thesaurus term： resolving power ,  lactate dehydrogenase ,  *infectious disease ,  antithrombin ,  *disseminated intravascular clotting ,  surveillance ,  lactam ,  polyene ,  vinyl compound ,  dicarboxylic acid
Semi thesaurus term： *臓器障害 ,  総ビリルビン ,  *トロンボモジュリンα ,  臨床的特徴 , 【Automatic Indexing@JST】

Author keywords (6)： DIC ,  Infectious disease ,  Hematological malignancy ,  SOFA ,  Bilirubin ,  Creatinine

JST classification (2)： Drug therapy(=pharmacotherapy)for hematologic diseases in general  (GK05020P) ,  Clinical application of drugs acting on blood and body fluid  (GW14020X)

Substance index (2)： Creatinine ,  Bilirubin

Reference (34)：

• N Engl J Med; Disseminated intravascular coagulation; M Levi, H Cate; 341; 1999; 586-592; 10.1056/NEJM199908193410807; citation_id=CR1
• Hematol Oncol Clin North Am; Disseminated intravascular coagulation current concepts of etiology, pathophysiology, diagnosis and treatment; RL Bick; 17; 2003; 149-176; 10.1016/S0889-8588(02)00102-8; citation_id=CR2
• Nat Rev Dis Primers; Disseminated intravascular coagulation; S Gando, M Levi, CH Toh; 2; 2016; 16037; 10.1038/nrdp.2016.37; citation_id=CR3
• J Intensive Care; Thrombomodulin/activated protein C system in septic disseminated intravascular coagulation; T Ikezoe; 3; 2015; 1; 10.1186/s40560-014-0050-7; citation_id=CR4
• Int J Hematol; Pathogenesis of disseminated intravascular coagulation in patients with acute promyelocytic leukemia, and its treatment using recombinant human soluble thrombomodulin; T Ikezoe; 100; 2014; 27-37; 10.1007/s12185-013-1463-0; citation_id=CR5

Terms in the title (10)： 感染症 ,  DIC ,  臓器不全 ,  血液悪性腫瘍 ,  トロンボモジュリンα ,  播種性血管内凝固 ,  治療 ,  転帰 ,  関連性 ,  分析