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J-GLOBAL ID：202002224455659899   Reference number：20A1436482

Oncolytic effect of Midkine promoter-based conditionally replicating adenoviruses expressing EGFR siRNA in head and neck squamous cancer cell line T891

頭頸部扁平上皮癌細胞株T891においてEGFR siRNAを発現するミッドカインプロモーターベース条件複製アデノウイルスの腫瘍崩壊効果【JST・京大機械翻訳】

Author (9)： Uehara Natsumi (Department of Otolaryngology-Head and Neck Surgery, Kobe University Graduate School of Medicine, Kobe, Japan) ,  Otsuki Naoki (Department of Otolaryngology-Head and Neck Surgery, Kobe University Graduate School of Medicine, Kobe, Japan) ,  Kubo Mie (Department of Otolaryngology-Head and Neck Surgery, Kobe University Graduate School of Medicine, Kobe, Japan) ,  Kitamoto Junko (Department of Otolaryngology-Head and Neck Surgery, Kobe University Graduate School of Medicine, Kobe, Japan) ,  Kojima Yasutaka (Department of Otolaryngology-Head and Neck Surgery, Kobe University Graduate School of Medicine, Kobe, Japan) ,  Teshima Masanori (Department of Otolaryngology-Head and Neck Surgery, Kobe University Graduate School of Medicine, Kobe, Japan) ,  Shinomiya Hirotaka (Department of Otolaryngology-Head and Neck Surgery, Kobe University Graduate School of Medicine, Kobe, Japan) ,  Shirakawa Toshiro (Division of Infectious Disease Control, Center for Infectious Disease, Kobe University Graduate School of Medicine, Kobe, Japan) ,  Nibu Ken-ichi (Department of Otolaryngology-Head and Neck Surgery, Kobe University Graduate School of Medicine, Kobe, Japan)
Material： Cancer Reports
Volume： 3  Issue： 3  Page： e1231  Publication year： 2020 
JST Material Number： W3665A  ISSN： 2573-8348  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Abstract/Point： BACKGROUND: Epidermal growth f...

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Thesaurus term： *Adenoviridae ,  antitumor action ,  adult (development) ,  *promoter (genetics) ,  cytotoxicity ,  gene expression ,  in vitro experiment ,  *EGF receptor ,  *siRNA ,  *Cell Line ,  *midkine ,  adenoviral vector ,  overexpression ,  *microorganism ,  *animal virus ,  molecular genetic phenomenon
Semi thesaurus term： 悪性腫瘍 ,  *頭頚部扁平上皮癌 , 【Automatic Indexing@JST】

Author keywords (5)： conditionally replicative adenovirus ,  EGFR ,  head and neck cancer ,  Midkine ,  siRNA

JST classification (1)： Chemistry,biochemistry and pathology of tumors(=neoplasms)  (GE02030N)

Terms in the title (8)： 頭頸部扁平上皮癌 ,  細胞株 ,  EGFR ,  siRNA ,  発現 ,  複製 ,  アデノウイルス ,  腫瘍崩壊