Art

J-GLOBAL ID：202002226615587269   Reference number：20A0514139

Effects of orally active hypoxia inducible factor alpha prolyl hydroxylase inhibitor, FG4592 on renal fibrogenic potential in mouse unilateral ureteral obstruction model

経口低酸素誘導因子αプロリルヒドロキシラーゼ阻害剤FG4592がマウス片側尿管閉塞モデルにおける腎臓線維形成能に及ぼす影響

Author (16)： Kabei Kazuya (Department of Applied Pharmacology and Therapeutics, Osaka City University Graduate School of Medicine, Asahimachi, Abeno-ku, Osaka, 545-8585, Japan) ,  Kabei Kazuya (Department of Urology, Osaka City University Graduate School of Medicine, Asahimachi, Abeno-ku, Osaka, 545-8585, Japan) ,  Kabei Kazuya (Minami-Osaka Hospital, Higashikagaya, Suminoe-ku, Osaka, 559-0012, Japan) ,  Tateishi Yu (Ishikiri Seiki Hospital, Yayoi-cho, Higashiosaka, Osaka, 579-8026, Japan) ,  Shiota Masayuki (Department of Research Support Platform, Osaka City University Graduate School of Medicine, Asahimachi, Abeno-ku, Osaka, 545-8585, Japan) ,  Osada-Oka Mayuko (Food Hygiene and Environmental Health Division of Applied Life Science, Graduate School of Life and Environmental Sciences, Kyoto Prefectural University, Sakyo-ku, Kyoto, 606-8522, Japan) ,  Nishide Shunji (Department of Urology, Osaka City University Graduate School of Medicine, Asahimachi, Abeno-ku, Osaka, 545-8585, Japan) ,  Nishide Shunji (Department of Pharmacology, Osaka City University Graduate School of Medicine, Asahimachi, Abeno-ku, Osaka, 545-8585, Japan) ,  Uchida Junji (Department of Urology, Osaka City University Graduate School of Medicine, Asahimachi, Abeno-ku, Osaka, 545-8585, Japan) ,  Nakatani Tatsuya (Department of Urology, Osaka City University Graduate School of Medicine, Asahimachi, Abeno-ku, Osaka, 545-8585, Japan) ,  Matsunaga Shinji (Department of Pharmacology, Osaka City University Graduate School of Medicine, Asahimachi, Abeno-ku, Osaka, 545-8585, Japan) ,  Yamaguchi Takehiro (Department of Pharmacology, Osaka City University Graduate School of Medicine, Asahimachi, Abeno-ku, Osaka, 545-8585, Japan) ,  Tomita Shuhei (Department of Pharmacology, Osaka City University Graduate School of Medicine, Asahimachi, Abeno-ku, Osaka, 545-8585, Japan) ,  Miura Katsuyuki (Department of Applied Pharmacology and Therapeutics, Osaka City University Graduate School of Medicine, Asahimachi, Abeno-ku, Osaka, 545-8585, Japan) ,  Miura Katsuyuki (Ishikiri Seiki Hospital, Yayoi-cho, Higashiosaka, Osaka, 579-8026, Japan) ,  Miura Katsuyuki (Department of Pharmacology, Osaka City University Graduate School of Medicine, Asahimachi, Abeno-ku, Osaka, 545-8585, Japan)
Material： Journal of Pharmacological Sciences (Web)  (J Pharmacol Sci (Web))
Volume： 142  Issue： 3  Page： 93-100  Publication year： 2020 
JST Material Number： U0667A  ISSN： 1347-8613  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Thesaurus term： transcription factor ,...
Semi thesaurus term： mRNA expression ,...

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Author keywords (4)： Hypoxia-inducible factor ,  Prolyl hydroxylase domain-containing protein ,  Renal fibrosis ,  FG-4592

JST classification (2)： Basic research of drugs acting on urinary system  (GW11010R) ,  Basic medicine on urogenital system  (GM01020T)

Substance index (1)： Roxadustat

Terms in the title (7)： 低酸素誘導因子 ,  プロリルヒドロキシラーゼ ,  阻害剤 ,  マウス ,  片側尿管閉塞 ,  モデル ,  腎臓