Art

J-GLOBAL ID：202002227239928334   Reference number：20A1357487

Oral Administration of Si-Based Agent Attenuates Oxidative Stress and Ischemia-Reperfusion Injury in a Rat Model: A Novel Hydrogen Administration Method

Si系薬剤の経口投与はラットモデルにおける酸化ストレスと虚血再灌流傷害を減弱する:新しい水素投与法【JST・京大機械翻訳】

Author (11)： Kawamura Masataka (Department of Urology, Osaka University Graduate School of Medicine, Suita, Japan) ,  Imamura Ryoichi (Department of Urology, Osaka University Graduate School of Medicine, Suita, Japan) ,  Kobayashi Yuki (The Institute of Scientific and Industrial Research, Osaka University, Ibaraki, Japan) ,  Taniguchi Ayumu (Department of Urology, Osaka University Graduate School of Medicine, Suita, Japan) ,  Nakazawa Shigeaki (Department of Urology, Osaka University Graduate School of Medicine, Suita, Japan) ,  Kato Taigo (Department of Urology, Osaka University Graduate School of Medicine, Suita, Japan) ,  Namba-Hamano Tomoko (Department of Nephrology, Osaka University Graduate School of Medicine, Suita, Japan) ,  Abe Toyofumi (Department of Urology, Osaka University Graduate School of Medicine, Suita, Japan) ,  Uemura Motohide (Department of Urology, Osaka University Graduate School of Medicine, Suita, Japan) ,  Kobayashi Hikaru (The Institute of Scientific and Industrial Research, Osaka University, Ibaraki, Japan) ,  Nonomura Norio (Department of Urology, Osaka University Graduate School of Medicine, Suita, Japan)
Material： Frontiers in Medicine (Web)
Volume： 7  Page： 95  Publication year： 2020 
JST Material Number： U7079A  ISSN： 2296-858X  Document type： Article
Article type： 原著論文  Country of issue： Switzerland (CHE)  Language： ENGLISH (EN)

Abstract/Point： Organ ischemia-reperfusion inj...

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Thesaurus term： *silicon ,  *hydrogen ,  gene ,  anti-inflammatory action ,  immunological reaction ,  *rat ,  active oxygen ,  polymerase chain reaction ,  apoptosis ,  *oxidative stress ,  immunohistochemistry ,  transcriptome
Semi thesaurus term： サイトカイン産生 ,  抗アポトーシス作用 , 【Automatic Indexing@JST】

Author keywords (6)： silicon ,  ischemia reperfusion injury ,  hydrogen ,  oxidative stress ,  kidney ,  rat

JST classification (2)： Basic medicine on urogenital system  (GM01020T) ,  Basic research of drugs acting on urinary system  (GW11010R)

Substance index (1)： 8-Hydroxy-2'-deoxyguanosine

Reference (33)：

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• Noiri E, Nakao A, Uchida K, Tsukahara H, Ohno M, Fujita T, et al. Oxidative and nitrosative stress in acute renal ischemia. Am J Physiol Renal Physiol. (2001) 281:F948-57. doi: 10.1152/ajprenal.2001.281.5.F948
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• Ohsawa I, Ishikawa M, Takahashi K, Watanabe M, Nishimaki K, Yamagata K, et al. Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals. Nat Med. (2007) 13:688-94. doi: 10.1038/nm1577

Terms in the title (10)： Si ,  薬剤 ,  経口投与 ,  ラット ,  モデル ,  酸化ストレス ,  虚血再灌流傷害 ,  減弱 ,  水素 ,  投与法