Art

J-GLOBAL ID：202002227933773464   Reference number：20A1336313

Regulatory T Cells: Pathophysiological Roles and Clinical Applications

調節性T細胞:病態生理学的役割と臨床応用

Author (5)： Sakai Ryota (Department of Microbiology and Immunology, Keio University School of Medicine, Tokyo, Japan) ,  Komai Kyoko (Department of Microbiology and Immunology, Keio University School of Medicine, Tokyo, Japan) ,  Iizuka-koga Mana (Department of Microbiology and Immunology, Keio University School of Medicine, Tokyo, Japan) ,  Yoshimura Akihiko (Department of Microbiology and Immunology, Keio University School of Medicine, Tokyo, Japan) ,  Ito Minako (Department of Microbiology and Immunology, Keio University School of Medicine, Tokyo, Japan)
Material： Keio Journal of Medicine  (Keio J Med)
Volume： 69  Issue： 1  Page： 1-15(J-STAGE)  Publication year： 2019 
JST Material Number： F0769A  ISSN： 0022-9717  CODEN： KJMEA9  Document type： Article
Article type： 文献レビュー  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *regulatory T cell ,...
Semi thesaurus term： genetic regulation ,...

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Author keywords (5)： regulatory T cell ,  epigenetics ,  GVHD ,  stroke ,  tissue repair

JST classification (2)： Basic neurology  (GN01020W) ,  Immunological reaction in general  (ED03010T)

Substance index (1)： Serotonin

Reference (143)：

• 1. Sakaguchi S, Yamaguchi T, Nomura T, Ono M: Regulatory T cells and immune tolerance. Cell 2008; 133: 775-787. PMID:18510923, DOI:10.1016/j.cell.2008.05.009
• 2. Bennett CL, Christie J, Ramsdell F, Brunkow ME, Ferguson PJ, Whitesell L, Kelly TE, Saulsbury FT, Chance PF, Ochs HD: The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3. Nat Genet 2001; 27: 20-21. PMID:11137993, DOI:10.1038/83713
• 3. Chatila TA, Blaeser F, Ho N, Lederman HM, Voulgaropoulos C, Helms C, Bowcock AM: JM2, encoding a fork head-related protein, is mutated in X-linked autoimmunity-allergic disregulation syndrome. J Clin Invest 2000; 106: R75-R81. PMID:11120765, DOI:10.1172/JCI11679
• 4. Wildin RS, Ramsdell F, Peake J, Faravelli F, Casanova JL, Buist N, Levy-Lahad E, Mazzella M, Goulet O, Perroni L, Dagna Bricarelli F, Byrne G, McEuen M, Proll S, Appleby M, Brunkow ME: X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy. Nat Genet 2001; 27: 18-20. PMID:11137992, DOI:10.1038/83707
• 5. Hori S, Nomura T, Sakaguchi S: Control of regulatory T cell development by the transcription factor Foxp3. Science 2003; 299: 1057-1061. PMID:12522256, DOI:10.1126/science.1079490

Terms in the title (5)： 調節性T細胞 ,  病態生理学 ,  役割 ,  臨床 ,  応用